Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Atezolizumab in addition to cobimetinib and vemurafenib for BRAF mutated metastatic melanoma	Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate) , Vemurafenib (Zelboraf; PLX4032; R7204; RO5185426; PLX-4032; RG7204)	Melanoma	Skin Cancer	2019	View \| Download
Atezolizumab in combination with cobimetinib for BRAF wild-type metastatic melanoma – first line	Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate)	Melanoma	Skin Cancer	2018	View \| Download
Bempegaldesleukin in combination with nivolumab for previously untreated unresectable or metastatic melanoma	Bempegaldesleukin (NKTR-214; BMS-986321; NEKTAR) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Melanoma	Skin Cancer	2022	View \| Download
Bifikafusp alfa-onfekafusp alfa neoadjuvant therapy for treating resectable stage IIIB and IIIC melanoma	Daromun	Melanoma	Skin Cancer	2023	View \| Download
Cemiplimab for advanced cutaneous squamous cell	Cemiplimab (Libtayo; REGN2810)	Squamous cell carcinoma (SCC)	Skin Cancer	2017	View \| Download
Dabrafenib with trametinib for treating metastatic or unresectable BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download
Dabrafenib with Trametinib with adjuvant therapy for treating advanced BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download
Elranatamab monotherapy or with daratumumab for previously treated relapsed or refractory multiple myeloma	Daratumumab (Darzalex; JNJ-54767414) , Elranatamab (PF-06863135)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas , Skin Cancer	2024	View \| Download
Lifileucel for unresectable or metastatic melanoma – second-line or greater	Lifileucel (Contego; LN-144) IB	Melanoma	Skin Cancer	2020	View \| Download
Nivolumab (Opdivo) for Melanoma after complete resection of Stage IIIb/c or Stage IV Melanoma (adjuvant therapy)	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Melanoma	Skin Cancer	2017	View \| Download