Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Ibrutinib with Venetoclax and Obinutuzumab for the treatment of Chronic Lymphocytic Leukaemia patients with TP53 deletion and/or mutation	Obinutuzumab (Gazyvaro; RO5072759; GA101; Afutuzumab) , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199)	Chronic lymphocytic leukaemia (CLL)	Haematological Cancer and Lymphomas	2017	View \| Download
Ibrutinib in combination with venetoclax for chronic lymphocytic leukaemia or small lymphocytic lymphoma – first line	Ibrutinib (Imbruvica) , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2020	View \| Download
Ibrutinib in combination with obinutuzumab for the treatment of chronic lymphocytic leukaemia/small lymphocytic lymphoma in elderly – first line	Ibrutinib (Imbruvica) , Obinutuzumab (Gazyvaro; RO5072759; GA101; Afutuzumab)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2017	View \| Download
Ibrutinib in addition to rituximab for chronic lymphocytic leukaemia – first-line	Ibrutinib (Imbruvica)	Chronic lymphocytic leukaemia (CLL)	Haematological Cancer and Lymphomas	2019	View \| Download
Ibrutinib for the treatment of relapsed or refractory follicular lymphoma	Ibrutinib (Imbruvica)	Follicular lymphoma	Haematological Cancer and Lymphomas	2017	View \| Download
Ibrutinib for chronic Graft versus Host Disease	Ibrutinib (Imbruvica)	Graft versus host disease (GvHD)	Immunology	2020	View \| Download
Ibalizumab in combination with other antiretroviral(s) for multidrug-resistant HIV-1 infection	Ibalizumab (Trogarzo; TNX-355)	HIV infection	Infectious Disease	2019	View \| Download
I-131-Apamistamab for acute myeloid leukaemia	I-131-Apamistamab (Iomab-B)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2023	View \| Download
Hydromethylthionine mesylate for Alzheimer's disease	Hydromethylthionine mesylate (LMTX;TRx-0237)	Alzheimer's disease	Neurology	2023	View \| Download
Human plasminogen for hypoplasminogenemia	Plasminogen (Ryplazim)	Hypoplasminogenaemia	Endocrine Nutritional and Metabolic Disorders	2018	View \| Download