Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Avapritinib for unresectable or metastatic gastrointestinal stromal tumours (GIST) who have been treated with at least 3 prior lines of therapy and GIST harbouring the PDGFRA D842V mutation regardless of prior therapy	Avapritinib (BLU-285; Ayvakit)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2019	View \| Download
Avatrombopag for chemotherapy induced thrombocytopenia in patients with nonhaematological cancers	Avatrombopag (Doptelet; E5501; avatrombopag maleate)	Chemotherapy-induced thrombocytopenia	Female Reproductive Cancer , Haematology , Lung and Respiratory Cancer , Toxicology , Urological Cancer	2020	View \| Download
Avatrombopag in addition to standard of care for chronic immune thrombocytopenia	Avatrombopag (Doptelet; E5501; avatrombopag maleate)	Immune thrombocytopenia (ITP)	Haematology , Immunology	2020	View \| Download
Avelumab for gastric and gastroesophageal junction adenocarcinoma – third line	Avelumab (Bavencio; MSB-0010718C)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2017	View \| Download
Avelumab for gastric or gastro-oesophageal junction cancer - first line maintenance	Avelumab (Bavencio; MSB-0010718C)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Avelumab in addition to best supportive care for locally advanced or metastatic urothelial cancer	Avelumab (Bavencio; MSB-0010718C)	Bladder cancer	Urological Cancer	2019	View \| Download
Avelumab in combination with axitinib for advanced or metastatic renal cell carcinoma – first line	Avelumab (Bavencio; MSB-0010718C) , Axitinib (Inlyta; AG-013736)	Renal cell carcinoma (RCC)	Renal Cancer	2018	View \| Download
Avelumab with or without Pegylated Liposomal Doxorubicin (PLD) for Ovarian Cancer – second line	Avelumab (Bavencio; MSB-0010718C) , Pegylated liposomal doxorubicin	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2018	View \| Download
AVXS-101 for spinal muscular atrophy	Onasemnogene abeparvovec (Zolgensma; AVXS-101; scAAV9.CB.SMN)	Spinal muscular atrophy (SMA)	Genetic Disorders , Musculoskeletal System	2018	View \| Download
Axalimogene Filolisbac for Cervical Cancer – Beyond First Line Treatment	Axalimogene filolisbac (ADXS11-001)	Cervical cancer	Female Reproductive Cancer	2018	View \| Download