Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
ABP 959 for treating paroxysmal nocturnal haemoglobinuria	ABP 959	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2022	View \| Download
ALXN 1210 for Paroxysmal Nocturnal Haemoglobinuria – First Line	Ravulizumab (ALXN1210; Ultomiris)	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2017	View \| Download
Apadamtase alfa for treating acute thrombotic thrombocytopenic purpura (TTP) episodes associated with congenital TTP (cTTP) and long-term prophylaxis in patients with congenital ADAMTS-13 deficiency	Apadamtase alfa	congenital ADAMTS-13 deficiency , Thrombotic thrombocytopenic purpura	Haematology	2022	View \| Download
Avatrombopag for chemotherapy induced thrombocytopenia in patients with nonhaematological cancers	Avatrombopag (Doptelet; E5501; avatrombopag maleate)	Chemotherapy-induced thrombocytopenia	Female Reproductive Cancer , Haematology , Lung and Respiratory Cancer , Toxicology , Urological Cancer	2020	View \| Download
Avatrombopag in addition to standard of care for chronic immune thrombocytopenia	Avatrombopag (Doptelet; E5501; avatrombopag maleate)	Immune thrombocytopenia (ITP)	Haematology , Immunology	2020	View \| Download
Bentracimab for reversal of the antiplatelet activity of ticagrelor	Bentracimab (PB2452)	Bleeding , Uncontrolled bleeding	Haematology	2021	View \| Download
Ciltacabtagene autoleucel for relapsed and refractory multiple myeloma	Ciltacabtagene Autoleucel (JNJ-68284528; LCAR-B38M CAR-T cell therapy; LCAR-B38M; JNJ 4528)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas , Haematology	2021	View \| Download
Concizumab for treating haemophilia A and haemophilia B	Concizumab (NN-7415; mAb-2021; NNC-0172-0000-2021; NNC-0172-2021; NNC-172-2021)	Haemophilia A , Haemophilia B	Haematology	2022	View \| Download
Crizanlizumab (formerly SelG1) for Sickle Cell Disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell anaemia	Haematology	2017	View \| Download
Crizanlizumab for the prevention of recurrent vaso-occlusive crises in children with sickle cell disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell disease (SCD)	Haematology	2022	View \| Download