Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 50 Results

Intervention Indication Therapeutic Area Year Actions
ABP 959 for treating paroxysmal nocturnal
ABP 959 Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2022 View  |  Download
ALXN 1210 for Paroxysmal Nocturnal Haemoglobinuria – First Line Ravulizumab (ALXN1210; Ultomiris) Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2017 View  |  Download
Apadamtase alfa for treating acute thrombotic thrombocytopenic purpura (TTP) episodes associated with congenital TTP (cTTP) and long-term prophylaxis in patients with congenital ADAMTS-13 deficiency Apadamtase alfa congenital ADAMTS-13 deficiency , Thrombotic thrombocytopenic purpura Haematology 2022 View  |  Download
Avatrombopag for chemotherapy induced thrombocytopenia in patients with nonhaematological cancers Avatrombopag (Doptelet; E5501; avatrombopag maleate) Chemotherapy-induced thrombocytopenia Female Reproductive Cancer , Haematology , Lung and Respiratory Cancer , Toxicology , Urological Cancer 2020 View  |  Download
Avatrombopag in addition to standard of care for chronic immune thrombocytopenia Avatrombopag (Doptelet; E5501; avatrombopag maleate) Immune thrombocytopenia (ITP) Haematology , Immunology 2020 View  |  Download
Bentracimab for reversal of the antiplatelet activity of ticagrelor Bentracimab (PB2452) Bleeding , Uncontrolled bleeding Haematology 2021 View  |  Download
Ciltacabtagene autoleucel for relapsed and refractory multiple myeloma Ciltacabtagene Autoleucel (JNJ-68284528; LCAR-B38M CAR-T cell therapy; LCAR-B38M; JNJ 4528) Multiple myeloma (MM) Haematological Cancer and Lymphomas , Haematology 2021 View  |  Download
Concizumab for treating haemophilia A and haemophilia B Concizumab (NN-7415; mAb-2021; NNC-0172-0000-2021; NNC-0172-2021; NNC-172-2021) Haemophilia A , Haemophilia B Haematology 2022 View  |  Download
Crizanlizumab (formerly SelG1) for Sickle Cell Disease Crizanlizumab (SEG101; Adakveo) Sickle cell anaemia Haematology 2017 View  |  Download
Crizanlizumab for the prevention of recurrent vaso-occlusive crises in children with sickle cell disease Crizanlizumab (SEG101; Adakveo) Sickle cell disease (SCD) Haematology 2022 View  |  Download
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