BI 907828 for previously untreated advanced dedifferentiated liposarcoma

BI 907828 is in clinical development for the first-line treatment of adults with advanced/metastatic dedifferentiated liposarcoma. Liposarcoma is a rare type of cancer that develops in the fatty tissues found all over the body. It can occur anywhere throughout the body but most commonly on the trunk, limbs and behind the abdomen. Dedifferentiated liposarcoma is an aggressive and high-grade form of liposarcoma. Advanced/metastatic cancer is cancer that has spread to the lymph nodes or other parts of the body and is not resectable (when the tumour cannot be removed by surgery). Liposarcoma occurs mainly in adults and is very rare in people under the age of 30. The current standard of care in the first-line treatment of patients with advanced dedifferentiated liposarcoma is associated with little efficacy and poor safety. There is need for more therapeutic options that will improve the lives of patients with advanced dedifferentiated liposarcoma.