Inhaled treprostinil for treating pulmonary hypertension with interstitial lung disease including combined pulmonary fibrosis and emphysema

Pulmonary hypertension is a rare and serious condition that occurs when blood pressure within the lungs becomes abnormally high. It can be caused by thickening of the pulmonary artery walls, heart failure, lung disease and clots within the lungs' blood vessels. Symptoms of pulmonary hypertension include shortness of breath, tiredness, feeling faint or dizzy, chest pain, a racing heartbeat, and swelling in the legs, ankles, feet, or abdomen. The symptoms often get worse during exercise. Pulmonary hypertension related with interstitial lung disease is associated with reduced exercise capacity, greater need for supplemental oxygen, decreased quality of life, and earlier death. There are currently no approved therapies for people with pulmonary hypertension associated with interstitial lung disease.