WP1048 for treating grass pollen allergy

WP1048 is in clinical development for the treatment of adults with grass pollen allergy. Grass pollen allergy, also known as hay fever or allergic rhinitis, is caused by an immune reaction to proteins found in pollen from various types of grass. The allergy presents symptoms such as itchy eyes, blocked and inflamed nose and persistent sneezing. This can confer a significant health burden on patients, as it affects daily functions such as sleep and concentration, thus affecting quality of life. Allergic rhinitis is greatly under-recognised and poorly managed, as there is a high prevalence rate in the UK. Management of grass pollen allergy is important to help improve patient clinical outcomes and quality of life as many patients often have co-morbidities associated with this allergy such as asthma and eczema, whose symptoms can be exacerbated in episodes of allergic reaction to grass pollen. Currently, most treatments for grass pollen allergy are not curative and are mainly focused on symptom relief.