Durvalumab is in clinical development for previously untreated patients with hepatocellular carcinoma (HCC), the most common type of liver cancer that develops in liver cells known as hepatocytes. Typically, this type of cancer occurs in patients with underlying chronic liver disease and scarring of the liver caused by long-term liver damage (cirrhosis), as a result […]
Epcoritamab is currently in development for treatment of diffuse large B-cell lymphoma (DLBCL).DLBCL is a cancer of B cells (a type of immune cell) and the most common type of fast-growingnon-Hodgkin’s lymphoma (NHL). In DLBCL, the body makes abnormal B cells which build up inlymph nodes or other body organs. The affected lymphocytes start to […]
The combination of sintilimab and pemetrexed and platinum chemotherapy is in clinical development for the treatment of advanced or metastatic non-squamous non-small cell lung cancer (NSCLC). NSCLC makes up the majority of lung cancers in the UK. Advanced cancers can be locally advanced or metastatic. Locally advanced NSCLC is when the cancer has grown into […]
Nivolumab is in clinical development for the adjuvant treatment of stage IB-IIIA non-small cell lung cancer (NSCLC). NSCLC occurs due to tumours forming in the lung and is the most common form of lung cancer. Stage IB-IIIA disease comprises of a range of tumours from 3cm to larger than 7cm in size and have little […]
Bimatoprost slow-release (implant) is currently in clinical development for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) who are unsuitable for topical IOP-lowering medications. OHT occurs when the IOP of the eye is raised and can cause glaucoma if untreated. Although OHT is a big risk factor […]
Nitazoxanide is in clinical development for the treatment of the common cold due to rhinovirus or other forms of enterovirus infection in adults and children aged 12 years and older. The common cold occurs amongst all population groups and most people will experience multiple infections a year. Currently, there are no treatment options approved to […]
Secukinumab is in clinical development for adult patients with moderate to severe hidradenitis suppurativa (HS). HS is a painful, long term skin condition that causes abscesses and scarring on the skin. The exact cause of HS is unknown, but it occurs near hair follicles where there are sweat glands, usually around the groin, bottom, breasts […]
Cabozantinib is being developed for the treatment of progressive differentiated thyroid cancer (DTC). Thyroid cancer is rare, and DTC is the most common type of this. It is usually found by a hard lump on the neck that does not move and may grow. It can cause a sore throat, neck pain, hoarseness, and difficulty […]
Baloxavir marboxil is in clinical development for the treatment of paediatric patients 1 to <12 years of age with influenza. Influenza or ‘flu’ is a common virus infection which causes high temperature, body aches, tiredness, cough, sore throat, headache, diarrhoea and nausea. Flu is usually spread by coughs and sneezes and occurs in annual flu […]
Merkel cell carcinoma (MCC) is a rare type of skin cancer that starts in neuroendocrine cells. Those frequently exposed to ultraviolet light and those with weakened immune systems are most at risk of developing MCC. Symptoms include lumps on the skin, usually found where the skin is most exposed to direct sun. MCC is an […]
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