Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Xevinapant with platinum-based chemoradiotherapy for previously untreated locally advanced squamous cell carcinoma of the head and neck	Xevinapant (Debio 1143; AT-406)	Head and neck cancer	Head and Neck Cancer	2022	View \| Download
Pembrolizumab in addition to platinum therapy and radiation for unresectable locally advanced head and neck squamous cell carcinoma	Cisplatin (Platinol) , Pembrolizumab (Keytruda; MK-3475)	Head and neck cancer	Head and Neck Cancer	2019	View \| Download
Nivolumab in combination with Ipilimumab for Recurrent or Metastatic Head and Neck Cancer – first line	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Head and neck cancer	Head and Neck Cancer	2018	View \| Download
Nivolumab in combination with chemoradiotherapy for squamous cell head and neck cancer	Cisplatin (Platinol) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Head and neck cancer	Head and Neck Cancer	2021	View \| Download
Nivolumab (Opdivo) with ipilimumab (Yervoy) for recurrent, metastatic, squamous cell head and neck cancer – first line	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Head and neck cancer	Head and Neck Cancer	2017	View \| Download
NBTXR3 (PEP-503) for head and neck squamous cell carcinoma in elderly patients	NBTXR3	Head and neck cancer	Head and Neck Cancer	2017	View \| Download
Leukocyte interleukin with cyclophosphamide, indomethacin, and zinc for neoadjuvant therapy of squamous cell carcinoma of the head and neck	Cyclophosphamide (Procytox; cyclophosphamide monohydrate) , Leukocyte interleukin (CS001P3; Multikine)	Head and neck cancer , Squamous cell carcinoma (SCC)	Head and Neck Cancer	2023	View \| Download
Lenvatinib with pembrolizumab for the treatment of squamous cell carcinoma of the head and neck	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Head and neck cancer , Squamous cell carcinoma (SCC)	Head and Neck Cancer	2022	View \| Download
Durvalumab in combination with Tremelimumab for recurrent or metastatic squamous cell carcinoma of the head and neck – first line	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Tremelimumab (CP-675206; CP-675 206)	Head and neck cancer	Head and Neck Cancer	2018	View \| Download
Durvalumab for recurrent or metastatic squamous cell carcinoma of the head and neck – first line	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736)	Head and neck cancer	Head and Neck Cancer	2019	View \| Download