Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Atezolizumab in addition to chemotherapy for small cell lung cancer – first line	Atezolizumab (Tecentriq; MPDL3280A)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2018	View \| Download
Durvalumab for limited stage small-cell lung cancer after 1 therapy	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2022	View \| Download
Durvalumab with or without tremelimumab in addition to platinum based chemotherapy for extensive-stage disease small-cell lung cancer	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Tremelimumab (CP-675206; CP-675 206)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2019	View \| Download
Durvalumab with tremelimumab for limited stage small-cell lung cancer	Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Tremelimumab (CP-675206; CP-675 206)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2022	View \| Download
Lurbinectedin in addition to doxorubicin for small-cell lung cancer after prior platinum-containing therapy	Doxorubicin (Livatag; BA-003; Caelyx; Sarcodoxome; SP-1049C; Resmycin; JNS002; doxorubicin hydrochloride) , Lurbinectedin (PM01183; Zepzelca)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2020	View \| Download
Lurbinectedin with atezolizumab maintenance therapy for extensive-stage small-cell lung cancer	Atezolizumab (Tecentriq; MPDL3280A) , Lurbinectedin (PM01183; Zepzelca)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab in addition to standard of care chemotherapy for extensive stage small cell lung cancer – first line	Pembrolizumab (Keytruda; MK-3475)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2018	View \| Download
Pembrolizumab with olaparib and chemoradiation for previously untreated limited-stage small-cell lung cancer	Chemoradiotherapy , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab-vibostolimab with etoposide and platinum chemotherapy for previously untreated extensive-stage small cell lung cancer	Etoposide , Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab) , Platinum-based chemotherapy	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Rovalpituzumab tesirine for the treatment of relapsed or refractory small cell lung cancer	Rovalpituzumab tesirine (SC16LD6.5; Rova-T)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2017	View \| Download