Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Dostarlimab with chemotherapy and niraparib for treating advanced epithelial ovarian cancers – first line	Chemotherapy , Dostarlimab (TSR-042; Jemperli) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Epithelial ovarian cancers	Female Reproductive Cancer	2023	View \| Download
Niraparib as maintenance therapy for treating recurrent or primary-advanced endometrial cancer after chemotherapy in combination with dostarlimab.	Chemotherapy , Dostarlimab (TSR-042; Jemperli) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download
Niraparib for advanced ovarian, fallopian tube or primary peritoneal cancer - maintenance therapy	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Niraparib for metastatic castration-resistant prostate cancer with DNA-repair anomalies	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Niraparib with abiraterone acetate and prednisone for metastatic castration resistant prostate cancer	Abiraterone acetate (Zytiga; Yonsa) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Niraparib with abiraterone acetate and prednisone for treating homologous recombination repair-mutated metastatic castration-sensitive prostate cancer	Abiraterone acetate (Zytiga; Yonsa) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2024	View \| Download
Niraparib with pembrolizumab maintenance therapy for metastatic stage III or IV non-small cell lung cancer	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download

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