Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Axicabtagene ciloleucel for relapsed/refractory diffuse large B-cell lymphoma – second-line	Axicabtagene Ciloleucel (Yescarta; KTE-C19)	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2019	View \| Download
Avelumab in addition to best supportive care for locally advanced or metastatic urothelial cancer	Avelumab (Bavencio; MSB-0010718C)	Bladder cancer	Urological Cancer	2019	View \| Download
Avelumab for gastric or gastro-oesophageal junction cancer - first line maintenance	Avelumab (Bavencio; MSB-0010718C)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Avapritinib for unresectable or metastatic gastrointestinal stromal tumours (GIST) who have been treated with at least 3 prior lines of therapy and GIST harbouring the PDGFRA D842V mutation regardless of prior therapy	Avapritinib (BLU-285; Ayvakit)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2019	View \| Download
Avalglucosidase alfa for late-onset Pompe disease	Avalglucosidase alfa (neoGAA; GZ-402666)	Pompe disease	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Atezolizumab in combination with bevacizumab for untreated unresectable or advanced hepatocellular carcinoma	Atezolizumab (Tecentriq; MPDL3280A) , Bevacizumab (Avastin; R 435; RG 405; RG 435)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2019	View \| Download
Atezolizumab in addition to paclitaxel, carboplatin and bevacizumab for epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer – first-line	Atezolizumab (Tecentriq; MPDL3280A) , Bevacizumab (Avastin; R 435; RG 405; RG 435) , Carboplatin (Paraplatin) , Paclitaxel (Taxol; paclitaxel albumin)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Atezolizumab in addition to paclitaxel for inoperable, locally advanced or metastatic triple negative breast cancer – first-line	Atezolizumab (Tecentriq; MPDL3280A) , Paclitaxel (Taxol; paclitaxel albumin)	Breast cancer	Breast Cancer	2019	View \| Download
Atezolizumab in addition to cobimetinib and vemurafenib for BRAF mutated metastatic melanoma	Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate) , Vemurafenib (Zelboraf; PLX4032; R7204; RO5185426; PLX-4032; RG7204)	Melanoma	Skin Cancer	2019	View \| Download
Atezolizumab for stage IV non-squamous or squamous non-small cell lung cancer	Atezolizumab (Tecentriq; MPDL3280A)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2019	View \| Download