Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Rovalpituzumab tesirine for the treatment of relapsed or refractory small cell lung cancer	Rovalpituzumab tesirine (SC16LD6.5; Rova-T)	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2017	View \| Download
Retifanlimab with chemotherapy for previously untreated metastatic non-small-cell lung cancer	Endocrine therapy , Ribociclib (Kisqali; LEE-011; ribociclib succinate)	Breast cancer , Non-small-cell lung cancer (NSCLC)	Breast Cancer , Lung and Respiratory Cancer	2024	View \| Download
Repotrectinib for treating advanced or metastatic nonsmall-cell lung cancer with ROS1-postive mutation	Repotrectinib (TPX 0005)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Ramucirumab in addition to erlotinib for EGFR mutation-positive metastatic non-small-cell lung cancer	Erlotinib (Tarceva; erlotinib hydrochloride) , Ramucirumab (Cyramza)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2019	View \| Download
Pralsetinib for RET-fusion positive metastatic non-small-cell lung cancer	Pralsetinib (BLU-667; Gavreto)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Plinabulin in addition to docetaxel for advanced, metastatic non-small-cell lung cancer - second line or greater	Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous) , Plinabulin (BPI-2358)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Pembrolizumab-vibostolimab with etoposide and platinum chemotherapy for previously untreated extensive-stage small cell lung cancer	Etoposide , Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab) , Platinum-based chemotherapy	Small-cell lung cancer (SCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab-vibostolimab for previously untreated non-small-cell lung cancer (NSCLC)	Pembrolizumab-vibostolimab (MK-7684; MK7684A; Vibostolimab)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Pembrolizumab with stereotactic body radiotherapy for unresected stage I or II non-small cell lung cancer	Pembrolizumab (Keytruda; MK-3475) , Stereotactic body radiotherapy	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Pembrolizumab with or without standard adjuvant therapy after resection for nonsmall-cell lung cancer - adjuvant	Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download