Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Crizotinib (Xalcori) for locally advanced or metastatic Non‐Small Cell Lung Cancer (NSCLC)	Crizotinib (Xalkori; PF-02341066; Xalkor)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2018	View \| Download
Crenolanib for Advanced or Metastatic Gastrointestinal Stromal Tumours (GISTs) with the D842V Mutation in the PDGFRA Gene	Crenolanib (CP-868; CP-868596)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2018	View \| Download
CER-001 for Familial Primary Hypoalphalipoproteinemia	CER-001	Familial primary hypoalphalipoproteinemia	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2018	View \| Download
Cenobamate for Partial Focal Epilepsy – Adjunctive Therapy	Cenobamate (YKP3089)	Epilepsy	Neurology	2018	View \| Download
Carotuximab in combination with Pazopanib for Advanced Angiosarcoma	Carotuximab (TRC105; DE-122) , Pazopanib (Votrient; GW 786034; pazopanib hydrochloride)	Soft tissue sarcoma	Sarcoma	2018	View \| Download
Brigatinib for locally advanced or metastatic, ALK-positive, non-small cell lung cancer – first line	Brigatinib (Alunbrig; AP26113)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2018	View \| Download
Brentuximab vedotin in addition to cyclophosphamide, doxorubicin, and prednisolone (CHP) for CD30+ mature T-cell lymphoma	Brentuximab vedotin (Adcetris; SGN-35) , CHP	Mature T-cell lymphoma	Haematological Cancer and Lymphomas	2018	View \| Download
BPX‐501 to improve Immune Recovery and Graft versus Host Disease (GvHD) after Haploidentical Stem Cell Transplant	Rivogenlecleucel (BPX-501)	Graft versus host disease (GvHD) , Immunodeficiency	Immunology	2018	View \| Download
Beraprost modified release in addition to treprostinil for pulmonary arterial hypertension	Esuberaprost (Beraprost-314d; BPS-314d-MR) , Treprostinil (Tyvaso; LIQ861; Orenitram; UT-15C; Remodulin; treprostinil sodium)	Pulmonary arterial hypertension (PAH)	Cardiovascular System , Respiratory System	2018	View \| Download
Bempedoic acid for primary hypercholesterolaemia or mixed dyslipidaemia in patients unable to reach cholesterol goals with the maximum tolerated dose of a statin	Bempedoic acid (ETC-1002; Nilemdo)	Mixed dyslipidaemia , Primary hypercholesterolaemia	Endocrine Nutritional and Metabolic Disorders	2018	View \| Download