Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 150 Results

Title
Intervention Indication Therapeutic Area Year Actions
Pembrolizumab addition to chemotherapy, followed by maintenance with olaparib for BRCA non-mutated advanced epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer – First-line Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475) Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer Female Reproductive Cancer 2020 View  |  Download
Pegunigalsidase alfa for Fabry disease – first-line PRX-102 (Pegunigalsidase alfa) Fabry disease Endocrine Nutritional and Metabolic Disorders , Genetic Disorders 2020 View  |  Download
Palbociclib for breast cancer - post neoadjuvant therapy Palbociclib (Ibrance; PD-0332991) Breast cancer Breast Cancer 2020 View  |  Download
Ozanimod for moderate to severe ulcerative colitis Ozanimod (RPC1063; Zeposia; ozanimod hydrochloride) Ulcerative colitis Gastroenterology 2020 View  |  Download
OTL-103 for Wiskott-Aldrich syndrome OTL-103 (GSK-2696275) Wiskott-Aldrich syndrome (WAS) Genetic Disorders , Immunology 2020 View  |  Download
Osimertinib for EGFR-positive non-small cell lung cancer - adjuvant Osimertinib (Tagrisso; AZD9291; osimertinib mesylate) Non-small-cell lung cancer (NSCLC) Lung and Respiratory Cancer 2020 View  |  Download
Oportuzumab monatox for non-muscle invasive bladder cancer - second line Oportuzumab monatox (Vicinium; VB4-845; Proxinium) Bladder cancer Urological Cancer 2020 View  |  Download
Omecamtiv mecarbil for treating chronic heart failure with reduced ejection fraction Omecamtiv Mecarbil (AMG 423; CK-1827452) Heart failure (HF) Cardiovascular System 2020 View  |  Download
Olaparib in addition to abiraterone for metastatic castration-resistant prostate cancer – First line Abiraterone acetate (Zytiga; Yonsa) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) Prostate cancer Male Reproductive Cancer 2020 View  |  Download
Olaparib for BRCA mutated and high risk HER2 negative breast cancer - adjuvant therapy Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) Breast cancer Breast Cancer 2020 View  |  Download
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