Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 145 Results

Clear All Filters

Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab in addition to trastuzumab and chemotherapy for HER2-positive advanced gastric or gastroesophageal junction adenocarcinoma – First-line	Pembrolizumab (Keytruda; MK-3475) , Trastuzumab (Herceptin; RG-597)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Pembrolizumab in addition to platinum therapy and radiation for unresectable locally advanced head and neck squamous cell carcinoma	Cisplatin (Platinol) , Pembrolizumab (Keytruda; MK-3475)	Head and neck cancer	Head and Neck Cancer	2019	View \| Download
Pembrolizumab in addition to cisplatin and fluorouracil for recurrent locally advanced or metastatic oesophageal cancer – First-line	5-Fluorouracil , Cisplatin (Platinol) , Pembrolizumab (Keytruda; MK-3475)	Oesophageal cancer	Head and Neck Cancer	2019	View \| Download
Pembrolizumab in addition to chemotherapy for perioperative treatment of gastric or gastro-oesophageal junction adenocarcinoma	FLOT , Pembrolizumab (Keytruda; MK-3475)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Pegcetacoplan (APL-2) for paroxysmal nocturnal haemoglobinuria	Pegcetacoplan (APL-2)	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2019	View \| Download
Palovarotene for flare-ups in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download
Palovarotene for episodic and chronic use in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download
OTL-200 for Metachromatic Leukodystrophy	OTL-200 (GSK-2696274)	Metachromatic leukodystrophy (MLD)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Onfekafusp alfa in addition to doxorubicin for advanced or metastatic soft tissue sarcoma – first line	Doxorubicin (Livatag; BA-003; Caelyx; Sarcodoxome; SP-1049C; Resmycin; JNS002; doxorubicin hydrochloride) , Onfekafusp alfa (L19-TNF; Fibromun)	Soft tissue sarcoma	Sarcoma	2019	View \| Download
Omalizumab for chronic rhinosinusitis with nasal polyps	Omalizumab (Xolair)	Rhinosinusitis	Ear Nose and Throat (ENT)	2019	View \| Download