Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Nivolumab in combination with ipilimumab for previously untreated unresectable or metastatic urothelial cancer – first-line	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Urothelial cancer	Urological Cancer	2020	View \| Download
Nivolumab in combination with ipilimumab for early stage non-small cell lung cancer -neoadjuvant	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Nivolumab in combination with chemotherapy for early-stage non-small cell lung cancer – neoadjuvant	Chemotherapy , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Nivolumab for hepatocellular carcinoma - adjuvant	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2020	View \| Download
Niraparib for metastatic castration-resistant prostate cancer with DNA-repair anomalies	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Naxitamab in combination with granulocyte-macrophage colony stimulation factor for relapsed/refractory high-risk neuroblastoma	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF; GM-CSF vaccine) , Naxitamab (Hu3F8; Danyelza)	Neuroblastoma	Neurological Cancer	2020	View \| Download
Mitapivat for treating pyruvate kinase deficiency	Mitapivat (AG-348)	Pyruvate kinase deficiency	Endocrine Nutritional and Metabolic Disorders	2020	View \| Download
Mepolizumab for hypereosinophilic syndrome – add-on therapy	Mepolizumab (Nucala; SB-240563; SB-240563 autoinjector)	Hypereosinophilic syndrome (HES)	Immunology	2020	View \| Download
Mepolizumab for chronic rhinosinusitis with nasal polyposis,in addition to standard care	Mepolizumab (Nucala; SB-240563; SB-240563 autoinjector)	Nasal polyps	Ear Nose and Throat (ENT)	2020	View \| Download
Melphalan flufenamide in combination with dexamethasone for treating adult patients with relapsed or refractory multiple myeloma	Dexamethasone (dexamethasone sodium metasulfobenzoate) , Melphalan flufenamide hydrochloride (Ygalo; Mel-flufen; J-1)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download