Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Avelumab for gastric or gastro-oesophageal junction cancer - first line maintenance	Avelumab (Bavencio; MSB-0010718C)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Avelumab for gastric and gastroesophageal junction adenocarcinoma – third line	Avelumab (Bavencio; MSB-0010718C)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2017	View \| Download
Avapritinib for unresectable or metastatic gastrointestinal stromal tumours (GIST) who have been treated with at least 3 prior lines of therapy and GIST harbouring the PDGFRA D842V mutation regardless of prior therapy	Avapritinib (BLU-285; Ayvakit)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2019	View \| Download
Atezolizumab with bevacizumab for patients with resected or ablated hepatocellular carcinoma who are at high risk for disease recurrence	Atezolizumab (Tecentriq; MPDL3280A) , Bevacizumab (Avastin; R 435; RG 405; RG 435)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2022	View \| Download
Atezolizumab in combination with bevacizumab for untreated unresectable or advanced hepatocellular carcinoma	Atezolizumab (Tecentriq; MPDL3280A) , Bevacizumab (Avastin; R 435; RG 405; RG 435)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2019	View \| Download
Atezolizumab (Tecentriq) and Cobimetinib (Cotellic) for advanced/metastatic colorectal cancer - third line	Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2017	View \| Download