Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 7 Results

Intervention Indication Therapeutic Area Year Actions
Atezolizumab (Tecentriq) and Cobimetinib (Cotellic) for advanced/metastatic colorectal cancer - third line Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate) Colorectal cancer Gastrointestinal Cancer , Oncology 2017 View  |  Download
Encorafenib in combination with binimetinib and cetuximab for BRAF V600E mutant metastatic colorectal cancer Binimetinib (MEK162; MEK-162; ARRY-162) , Cetuximab (Erbitux; STI-001) , Encorafenib (LGX818) Colorectal cancer Gastrointestinal Cancer , Oncology 2019 View  |  Download
Favezelimab-pembrolizumab for treating metastatic PD-L1 positive colorectal cancer Favezelimab-pembrolizumab Colorectal cancer Gastrointestinal Cancer , Oncology 2023 View  |  Download
Pembrolizumab for Stage IV Colorectal Carcinoma – first line Pembrolizumab (Keytruda; MK-3475) Colorectal cancer Gastrointestinal Cancer , Oncology 2018 View  |  Download
Pembrolizumab with lenvatinib for previously treated metastatic colorectal cancer Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475) Colorectal cancer Gastroenterology , Oncology 2022 View  |  Download
TAS-102 with bevacizumab for treating refractory metastatic colorectal cancer after 2 previous therapies Bevacizumab (Avastin; R 435; RG 405; RG 435) , Lonsurf; TAS-102 (fixed dose combination: Trifluridine; Tipiracil hydrochloride) Colorectal cancer Gastrointestinal Cancer , Oncology 2023 View  |  Download
Tucatinib with trastuzumab for treating colorectal cancer Trastuzumab (Herceptin; RG-597) , Tucatinib (ONT-380) Colorectal cancer Gastrointestinal Cancer 2022 View  |  Download
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