Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Tucatinib with trastuzumab for treating colorectal cancer	Trastuzumab (Herceptin; RG-597) , Tucatinib (ONT-380)	Colorectal cancer	Gastrointestinal Cancer	2022	View \| Download
TAS-102 with bevacizumab for treating refractory metastatic colorectal cancer after 2 previous therapies	Bevacizumab (Avastin; R 435; RG 405; RG 435) , Lonsurf; TAS-102 (fixed dose combination: Trifluridine; Tipiracil hydrochloride)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2023	View \| Download
Pembrolizumab with lenvatinib for previously treated metastatic colorectal cancer	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Colorectal cancer	Gastroenterology , Oncology	2022	View \| Download
Pembrolizumab for Stage IV Colorectal Carcinoma – first line	Pembrolizumab (Keytruda; MK-3475)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2018	View \| Download
Fruquintinib for treating refractory metastatic colorectal cancer	Fruquintinib (Elunate; TAK113; HMPL013)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2023	View \| Download
Favezelimab-pembrolizumab for treating metastatic PD-L1 positive colorectal cancer	Favezelimab-pembrolizumab	Colorectal cancer	Gastrointestinal Cancer , Oncology	2023	View \| Download
Encorafenib in combination with binimetinib and cetuximab for BRAF V600E mutant metastatic colorectal cancer	Binimetinib (MEK162; MEK-162; ARRY-162) , Cetuximab (Erbitux; STI-001) , Encorafenib (LGX818)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2019	View \| Download
Atezolizumab (Tecentriq) and Cobimetinib (Cotellic) for advanced/metastatic colorectal cancer - third line	Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2017	View \| Download

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