A traumatic cervical spinal cord injury results from trauma (such as a fall or car crash, rather than from a disease), and affects the spinal cord in the upper part of the spine (known as the cervical spine). The spinal cord is the bundle of nerves that runs down the middle of the back, and […]
ABBV-951 is currently in clinical development for the treatment of motor fluctuations in Parkinson’s Disease (PD). PD is a progressive neurological disease which is caused by a loss of nerve cells in a particular part of the brain and a reduction in the levels of the chemical messenger dopamine. Loss of these nerve cells and […]
Abemaciclib is in clinical development as an adjuvant treatment for patients with early breast cancer who have undergone surgery. Early breast cancer is where the disease is limited to the breast region and has not spread to other parts of the body. Symptoms include swelling of breast regions, breast or nipple pain, nipple retraction, change […]
Abicipar pegol is an anti‐VEGF‐A therapy in clinical development for the treatment of wet age‐related macular degeneration. Wet age‐related macular degeneration is a chronic eye disease characterised by the formation and proliferation of blood vessels in the centre of the retina (a layer of tissue in the back of the eye that senses light and […]
Abilify MyCite (aripiprazole with sensor) is in clinical development for the treatment of adults with Bipolar Disorder (BP1) and Schizophrenia (SCH). BP1 is a mental health condition that causes high and low mood swings that go on for longer periods of time, compared to usual fluctuations in mood. SCH can result in a person having […]
Abrocitinib is in development for the treatment of moderate to severe atopic dermatitis (AD) in adolescents and adults aged 12 years or over. AD is a chronic inflammatory skin disease that affects both children and adults and is characterised by redness, itchiness, and scaling of the skin. Some people only have small patches of dry […]
Status epilepticus is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to baseline between them. Status epilepticus is categorized as early, established, refractory and super-refractory. Patients with refractory status epilepticus (RSE) have failed first and second line agents (typically benzodiazepines and […]
The treatment, rexmyelocel-T, is being developed to relieve leg pain at rest and heal leg ulcers. The treatment uses cells from bone marrow which are injected into the damaged blood vessel, where they restore existing blood vessels and create new blood vessels. By improving the blood flow in the limb, this treatment aims to improve […]
131I-omburtamab is a medicinal product that is being developed for the treatment of children with advanced neuroblastoma that has spread to membranes lining the brain and spinal cord (‘leptomeningeal metastasis’). Neuroblastoma is a rare cancer that mostly affects babies and young children. It develops from specialised nerve cells (neuroblasts) in the foetus that do not […]
177Lu-PSMA-617 is in clinical development for patients with metastatic castrationresistant prostate cancer (mCRPC) who have been previously treated with androgen receptor-directed therapy (ARDT) and a taxane-based chemotherapy. Prostate cancer is a cancer of the prostate gland and mCRPC is when the cancer has spread to parts of the body other than the prostate, and it […]
Subscribe to new content email alerts
Email *
Interested groups * Achondroplasia Activated PI3K delta syndrome Acute hepatic porphyria (AHP) Acute ischaemic stroke Acute lymphoblastic leukaemia (ALL) Acute myeloid leukaemia (AML) Adrenoleukodystrophy (ALD) Adrenomyeloneuropathy (AMN) Advanced dedifferentiated liposarcoma Age-related macular degeneration (AMD) Alagille syndrome Alcohol use disorder Alkaptonuria Alopecia areata Alport Syndrome Alzheimer's disease Amyloid light chain amyloidosis Amyloidosis Amyotrophic lateral sclerosis Anaemia Anaemia due to myelodysplastic syndromes (MDS) Anaemic myelofibrosis Anaesthesia Anal cancer Anaplastic astrocytoma Anaplastic large cell lymphoma (ALCL) Aneurysmal subarachnoid haemorrhage Angioimmunoblastic T-cell Lymphoma (AITL) Ankylosing spondylitis Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) Aromatic L-amino acid decarboxylase (AADC) deficiency Arterial venous access Articular cartilage defects Asthma Atopic dermatitis Atypical haemolytic uraemic syndrome (aHUS) Axial spondyloarthritis B-cell non-Hodgkin lymphoma Back pain Benign prostatic hyperplasia (BPH) Beta thalassemia Biliary atresia Biliary tract cancer Bipolar disorder Bladder cancer Bladder pain syndrome Blastic plasmacytoid dendritic cell neoplasm (BPDCN) Bleeding Bone and Cartilage Cancer Bone sarcoma Breast cancer Bronchiectasis Bronchiolitis obliterans Bullous pemphigoid Calciphylaxis Canagliflozin (Invokana;JNJ-28431754) Cancer pain Cardiovascular disease (CVD) Cardiovascular events Cardiovascular System Cervical cancer Charcot-Marie-Tooth disease Chemoradiation-induced oral mucositis Chemotherapy-induced neutropenia Chemotherapy-induced thrombocytopenia Cholangiocarcinoma Choroideremia Chronic hand eczema Chronic heart failure Chronic hepatitis D Chronic idiopathic constipation (CIC) Chronic inducible cold urticaria Chronic inflammatory demyelinating polyradiculoneuropathy Chronic kidney disease (CKD) Chronic lymphocytic leukaemia (CLL) Chronic myeloid leukaemia (CML) Chronic myelomonocytic leukaemia (CMML) Chronic obstructive pulmonary disease (COPD) Chronic spontaneous urticaria (CSU) Chronic thromboembolic pulmonary hypertension (CTEPH) Clostridioides difficile infection Cognitive impairment Cold agglutinin disease (CAD) Colon cancer Colorectal cancer Common cold Community-acquired pneumonia Complement 3 glomerulopathy Complex regional pain syndrome (CRPS) congenital ADAMTS-13 deficiency Congenital heart disease Congenital hyperinsulinism COVID-19 Critical limb ischaemia (CLI) Crohn's disease Cutaneous T-cell lymphoma (CTCL) Cystic fibrosis Cystinuria Cytomegalovirus (CMV) Delayed graft function (DGF) Dental and Oral Health Depression Dermatology Dermatomyositis Desmoid Tumour Diabetic foot ulcer (DFU) Diabetic macular oedema Diabetic nephropathy Diabetic retinopathy Differentiated thyroid cancer (DTC) Diffuse large B-cell lymphoma (DLBCL) Distal renal tubular acidosis Duchenne muscular dystrophy (DMD) Dupuytren's disease Dystrophic epidermolysis bullosa (DEB) Ear Endometrial cancer Endometriosis-associated pain Enthesitis-related arthritis Eosinophilic granulomatosis Eosinophilic granulomatosis with polyangiitis Eosinophilic oesophagitis Epilepsy Epithelial ovarian cancer Epithelial ovarian cancers Erectile dysfunction Erythropoietic protoporphyria Exocrine pancreatic insufficiency (EPI) Fabry disease Facial angiofibroma Fallopian tube cancer Familial adenomatous polyposis (FAP) Familial chylomicronaemia syndrome (FCS) Familial primary hypoalphalipoproteinemia Fatal Female Reproductive Cancer Fibrodysplasia ossificans progressiva Focal segmental glomerulosclerosis (FSGS) Follicular lymphoma Friedreich's ataxia Fungal infections Gastric cancer Gastro-oesophageal junction adenocarcinoma Gastro-oesophageal junction cancer Gastroenteropancreatic neuroendocrine tumour Gastroesophageal adenocarcinoma Gastrointestinal Cancer Gastrointestinal stromal tumour (GIST) Gaucher disease Generalised pustular psoriasis Generalised pustular psoriasis flares Genetic Disorders Geographic atrophy Giant cell arteritis Glaucoma Glioma Glucose transporter type 1 deficiency syndrome Glycogen storage disease type 1a GM1 gangliosidosis GM2 gangliosidosis Graft versus host disease (GvHD) Granulomatosis with polyangiitis (GPA) Grass pollen allergy Gynaecology and Obstetrics Haemophilia A Haemophilia B Hand dysfunction Head and neck cancer Heart failure (HF) Heavy menstrual bleeding Helicobacter pylori Hepatocellular carcinoma (HCC) Hereditary angioedema (HAE) Heterozygous familial hypercholesterolaemia (HeFH) Hidradenitis suppurativa (HS) High grade B cell lymphoma (HGBCL) HIV infection HIV-1 infection Hodgkin lymphoma Homozygous familial hypercholesterolemia Hospital-acquired pneumonia Hot flushes Huntington's disease Hyperargininemia Hypereosinophilic syndrome (HES) Hyperlipidaemia Hyperphagia Hypersomnia Hypertension Hypertrophic cardiomyopathy (HCM) Hypoglycaemia Hypoparathyroidism Hypophosphataemia Hypoplasminogenaemia Hypothalamic obesity Idiopathic chronic cough Idiopathic inflammatory myopathies Idiopathic pulmonary fibrosis Idiopathic thrombocytopenic purpura IgA nephropathy Immune thrombocytopenia (ITP) Immunodeficiency Influenza Inherited epidermolysis bullosa (EB) Injured gluteal musculature Insomnia Interstitial cystitis Interstitial lung disease (ILD) Invasive candidasis Iron deficiency Iron overload Irritable bowel syndrome with predominant constipation (IBS-C) Ischaemic stroke Juvenile idiopathic arthritis Juvenile psoriatic arthritis Keratoconjunctivitis sicca (dry eye disease) Leber's hereditary optic neuropathy (LHON) Lennox-Gastaut syndrome Leukocyte adhesion deficiency Long chain fatty acid oxidation disorders (LC-FAOD) Lower limb spasticity Lupus nephritis Lymphoblastic lymphoma (LBL) Lymphocytic colitis Major adverse cardiovascular events (MACE) Major cardiovascular events Major depressive disorder (MDD) Malignant hyperthermia Malignant pleural mesothelioma (MPM) Mantle cell lymphoma Marginal zone lymphoma (MZL) Mature T-cell lymphoma Medullary thyroid cancer (MTC) Melanoma Merkel cell carcinoma (MCC) Metabolic acidosis Metabolic Disorders Metachromatic leukodystrophy (MLD) Methotrexate toxicity during cancer therapy Microscopic polyangiitis (MPA) Migraine Mixed dyslipidaemia Molybdenum cofactor deficiency Type A Monocarboxylate transporter 8 deficiency (Allan-Herndon-Dudley syndrome) Motor neurone disease (MND or ALS) Mucopolysaccharidosis type IIIB (Sanfilippo B syndrome) Mucopolysaccharidosis type VII Multifocal motor neuropathy Multiple myeloma (MM) Multiple sclerosis (MS) Muscle spasticity Myasthenia gravis (MG) Myelodysplastic syndrome (MDS) Myelofibrosis Myeloproliferative Neoplasms Myofibroblastic tumour Myopia Myotonia Myotonic dystrophy Myxoid round cell liposarcoma Narcolepsy Nasal polyps Nasopharyngeal cancer Nasopharyngeal carcinoma Neovascular age-related macular degeneration Neuroblastoma Neurofibromatosis Neurogenic detrusor overactivity Neuromyelitis optica Neuromyelitis optica spectrum disorders Niemann-Pick Disease Nocturia Non-alcoholic steatohepatitis (NASH) Non-gBRCA mutated high-grade serous ovarian cancer Non-Hodgkin lymphoma (NHL) Non-malignant diseases Non-metastatic prostate cancer Non-small-cell lung cancer (NSCLC) Nose and Throat Obesity Obesity due to heart-failure Obesity due to Leptin receptor deficiency Obesity due to pro-opiomelanocortin deficiency Obesity-related heart failure Ocular hypertension Ocular inflammatory pain Oesophageal cancer Oesophageal squamous cell cancer Oesophageal squamous cell carcinoma Opioid dependence Opioid overdose Oral ulcers Orthostatic hypotension Osteoarthritic pain Osteomalacia Osteoporosis Ovarian cancer Ovarian function Overactive bladder Painful bladder syndrome Pancreatic cancer Parkinson's disease Paroxysmal nocturnal haemoglobinuria Paroxysmal nocturnal haemoglobinuria (PNH) Peanut allergy Pemphigus foliaceus Pemphigus vulgaris Peripheral arterial disease (PAD) Peripheral T-cell lymphoma (PTCL) PIK3CA-related overgrowth spectrum (PROS) Plaque psoriasis Plexiform neurofibromas Polycythaemia vera Pompe disease Post-acute myocardial infarction (MI) Post-menopausal vasomotor symptoms Post-operative inflammation Post-operative pain Post-transplant lymphoproliferative disease (PTLD) Postmenopausal osteoporosis Postnatal depression Postpartum depression Pouchitis Prevention of skeletal related events in multiple myeloma Primary biliary cholangitis (PBC) Primary generalised tonic-clonic seizures Primary haemophagocytic lymphohistiocytosis (HLH) Primary hypercholesterolaemia Primary hyperoxaluria Primary mediastinal large B-cell lymphoma (PMBCL) Primary open-angle glaucoma primary peritoneal cancer Primary sclerosing cholangitis (PSC) Procedural sedation Progeria Progressive familial intrahepatic cholestasis (PFIC) Progressive fibrosing interstitial lung disease (PF-ILD) Progressive pulmonary fibrosis Progressive supranuclear palsy (PSP) Prostate cancer Prurigo nodularis (PN) Pruritus Psoriatic arthritis Pulmonary arterial hypertension (PAH) Pulmonary hypertension Pyruvate kinase deficiency Regeneration of cartilage Renal anaemia Renal cell carcinoma (RCC) Renal disease Resistant hypertension Respiratory dysfunction Retinal Vein Occlusion Retinitis pigmentosa Retinopathy of prematurity Rett syndrome Rheumatoid arthritis Rhinosinusitis Schizophrenia Schnitzler syndrome Serious Trouble Short bowel syndrome Sialorrhea Sickle cell anaemia Sickle cell disease (SCD) Small lymphocytic lymphoma (SLL) Small-cell lung cancer (SCLC) Soft tissue sarcoma Solid tumours Spasmodic torticollis Spinal cord injury Spinal muscular atrophy (SMA) Spinocerebellar ataxia Spondyloarthritis Squamous cell carcinoma (SCC) Stroke Sudden sensorineural hearing loss Super-refractory status epilepticus (SRSE) Synovial sarcoma Systemic lupus erythematosus (SLE) Systemic mastocytosis Systemic sclerosis Tendon injury Tenosynovial giant cell tumour (TGCT) Thromboembolism Thrombotic microangiopathies Thrombotic thrombocytopenic purpura Thyroid cancer Thyroid eye disease (TED) Transthyretin amyloid cardiomyopathy Transthyretin-mediated amyloid polyneuropathy Traumatic brain injury (TBI) Tree pollen allergy Tuberous sclerosis Type 1 diabetes Type 2 diabetes Ulcerative colitis Ulcerative proctitis Uncontrolled bleeding Upper limb spasticity Urinary incontinence Urothelial cancer Uterine Fibroids Uveal melanoma Venous leg ulcers Ventilator-associated pneumonia Visual impairment Vitiligo von Willebrand disease Weight management WHIM syndrome Wilson's disease Wiskott-Aldrich syndrome (WAS) X-linked adrenoleukodystrophy (X-ALD) X-linked protoporphyria Check All
By clicking "subscribe" I confirm that I am happy to receive alerts.
Subscribed successfully.