Avatrombopag is in clinical development for the treatment of chemotherapy-induced thrombocytopenia (CIT) in patients with active non-haematological cancers. CIT refers to abnormally low platelet (type of blood cells) count, with or without bleeding, in cancer patients receiving myelosuppressive chemotherapy (treatment that stops or slows the growth of blood-forming cells in the bone marrow). Most chemotherapy […]
Atezolizumab in combination with bevacizumab is currently in clinical development for the treatment of patients with an unresectable or advanced type of liver cancer called hepatocellular carcinoma (HCC) that have not received previous treatment. HCC is the most common type of liver cancer and occurs mainly in patients with underlying chronic liver disease and cirrhosis. […]
Atezolizumab in combination with chemotherapy is in clinical development as a neoadjuvant and adjuvant treatment for stage II, IIIA, or select IIIB non-small-cell lung cancer (NSCLC). NSCLC is the most common type of lung cancer. Early-stage lung cancer is typically treated with surgery consisting of removing either part of or the whole of the lung, […]
Atezolizumab is being investigated in addition to other chemotherapy (carboplatin and etoposide) as an initial (first-line) treatment for patients with extensive stage small cell lung cancer (ES-SCLC). SCLC is one of the two main types of lung cancer and the ES-SCLC means that the cancer has spread beyond a single area that can be treated […]
Atezolizumab is currently in clinical development for the treatment of patients muscle-invasive urothelial cancer (MIUC) including muscle-invasive bladder cancer (MIBC) and upper tract urothelial cancer (UTUC) patients who are at high risk following resection. MIBC is a cancer that spreads into the thick muscle deep in the bladder wall. MIBC starts in the inner bladder […]
Atezolizumab is in clinical development as an adjuvant treatment for resectable non-small cell lung cancer (NSCLC). An adjuvant treatment is an additional treatment given after primary treatment that aims to reduce risk of disease recurrence. Lung cancer is one of the most common and serious types of cancer and NSCLC is the most common type […]
Atezolizumab is in clinical development for stage IV non-squamous or squamous non small cell lung cancer (NSCLC). NSCLC makes up the majority of lung cancers in the UK. Stage IV (advanced/metastatic) NSCLC is when the cancer has spread beyond the lung which was initially affected, most often to the liver, the adrenal glands, the bones, […]
Atezolizumab is in clinical development, in combination with platinum-based chemotherapy, for the treatment of patients with locally advanced or metastatic urothelial cancer, who have received no prior systemic therapy (a drug which travels through the bloodstream and affects the whole body). Urothelial cancer, a subset of bladder cancer, occurs on the lining of the bladder, […]
Atezolizumab as an intravenous infusion, which in combination with an intravenous infusion of nab-paclitaxel, is in clinical development for the treatment of unresectable, locally advanced or triple-negative metastatic breast cancer (TNBC). TNBC is an uncommon type of breast cancer in which the cancer cells do not express receptors for oestrogen or progesterone or HER2 protein. […]
Atezolizumab in addition to carboplatin, paclitaxel and bevacizumab, is in clinical development for epithelial ovarian, fallopian tube or primary peritoneal cancer. Ovarian cancer includes a group of tumours that arise from the ovary. The most common type of ovarian cancer arises from the outside layer of cells on the surface of the ovary. Fallopian tube […]
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