AR101 is a form of treatment for peanut allergy. This treatment is administered orally with the aim of reeducatingthe body's immune system, in order to increase the level at which the body reacts to peanuts, or toreduce the allergic response. The drug is targeted at adults and children with severe peanut allergy.Phase III clinical trials […]
Arimoclomol is a medicine that is under investigation as a treatment for NPC. It is given by mouth as capsules. Arimoclomol helps the body’s cells to process accumulated lipids. If licensed, arimoclomol could offer an additional treatment option for people with NPC.
Asciminib is in clinical development as a third line therapy for adult patients with chronic phase chronic myeloid leukaemia (CML) who have been previously treated with two or more tyrosine kinase inhibitors (TKI). CML is a slowly developing cancer that arises due to the production of abnormal immune cells known as white blood cells. In […]
Age-related macular degeneration (AMD) is a major cause of visual impairment in older adults in the UK. It has three stages - early, intermediate, and late - and can occur in one or both eyes. It is possible for one eye to be at the early stage and the other at late stage. There are […]
Alpelisib is a new drug that is being developed for patients with the HR+/HER2- type of advanced breast cancer. The drug is being developed to be given in combination with fulvestrant, a drug that is already in use for the treatment of advanced breast cancer. Alpelisib targets a very specific enzyme that transmits signals to […]
AMG 510 is in clinical development for the treatment of adults with KRASG12C mutated, metastatic non-small cell lung cancer (NSCLC). NSCLC is the most common form of lung cancer and a small proportion of patients with NSCLC have tumours which carry the genetic mutation KRASG12C. Metastatic NSCLC describes tumours that have spread from the lungs […]
Amivantamab is in clinical development in the treatment of patients with advanced non-small-cell lung cancer (NSCLC) who have previously been treated with platnum-based chemotherapy. NSCLC makes up the majority of lung cancers in the UK. Metastatic NSCLC is when the cancer has spread beyond the lung that was initially affected, most often to the liver, […]
Anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumour (IMT) are both rare conditions that usually affect children and young adults. ALCL is a type of cancer that occurs when T-cells, which contribute to the body’s immune system, become abnormal. IMTs are most commonly non-cancerous (benign), however in some cases the tumour can become cancerous […]
Angioedema is a rare blood disorder characterised by rapid swelling below the skin. Most often affect are hands, feet, eyes, lips or genitals. The swelling is caused by a collection of fluid in the deep layers of the skin. Hereditary Angioedema (HAE) is a rare condition caused by mutations that reduce the production or expression […]
Angiotensin II acetate is in clinical development for the treatment of catecholamine and/or vasopressin resistant hypotension due to distributive shock. Shock is a critical condition in which blood pressure drops so low that the brain, kidneys and other vital organs cannot receive enough blood flow to function properly. Distributive shock is the most common type […]
Subscribe to new content email alerts
Email *
Interested groups * Achondroplasia Activated PI3K delta syndrome Acute hepatic porphyria (AHP) Acute ischaemic stroke Acute lymphoblastic leukaemia (ALL) Acute myeloid leukaemia (AML) Adrenoleukodystrophy (ALD) Adrenomyeloneuropathy (AMN) Advanced dedifferentiated liposarcoma Age-related macular degeneration (AMD) Alagille syndrome Alcohol use disorder Alkaptonuria Allergic rhinitis Allergic rhinoconjunctivitis Alopecia areata Alport Syndrome Alzheimer's disease Amyloid light chain amyloidosis Amyloidosis Amyotrophic lateral sclerosis Anaemia Anaemia due to myelodysplastic syndromes (MDS) Anaemic myelofibrosis Anaesthesia Anal cancer Anaplastic astrocytoma Anaplastic large cell lymphoma (ALCL) Aneurysmal subarachnoid haemorrhage Angioimmunoblastic T-cell Lymphoma (AITL) Ankylosing spondylitis Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) Aromatic L-amino acid decarboxylase (AADC) deficiency Arterial venous access Articular cartilage defects Asthma Atopic dermatitis Atypical haemolytic uraemic syndrome (aHUS) Axial spondyloarthritis B-cell non-Hodgkin lymphoma Back pain Benign prostatic hyperplasia (BPH) Beta thalassemia Biliary atresia Biliary tract cancer Bipolar disorder Bladder cancer Bladder pain syndrome Blastic plasmacytoid dendritic cell neoplasm (BPDCN) Bleeding Bone and Cartilage Cancer Bone sarcoma Breast cancer Bronchiectasis Bronchiolitis obliterans Bullous pemphigoid C3 glomerulopathy Calciphylaxis Canagliflozin (Invokana;JNJ-28431754) Cancer pain Cardiovascular disease (CVD) Cardiovascular events Cardiovascular System Cervical cancer Charcot-Marie-Tooth disease Chemoradiation-induced oral mucositis Chemotherapy-induced neutropenia Chemotherapy-induced thrombocytopenia Cholangiocarcinoma Choroideremia Chronic anal fissure Chronic cough Chronic hand eczema Chronic heart failure Chronic hepatitis D Chronic idiopathic constipation (CIC) Chronic inducible cold urticaria Chronic inflammatory demyelinating polyradiculoneuropathy Chronic kidney disease (CKD) Chronic lymphocytic leukaemia (CLL) Chronic myeloid leukaemia (CML) Chronic myelomonocytic leukaemia (CMML) Chronic obstructive pulmonary disease (COPD) Chronic spontaneous urticaria (CSU) Chronic thromboembolic pulmonary hypertension (CTEPH) Clostridioides difficile infection Cluster headache Cognitive impairment Cold agglutinin disease (CAD) Colon cancer Colorectal cancer Common cold Community-acquired pneumonia Complement 3 glomerulopathy Complex regional pain syndrome (CRPS) congenital ADAMTS-13 deficiency Congenital heart disease Congenital hyperinsulinism COVID-19 Critical limb ischaemia (CLI) Crohn's disease Cutaneous T-cell lymphoma (CTCL) Cystic fibrosis Cystinuria Cytomegalovirus (CMV) Delayed graft function (DGF) Dental and Oral Health Depression Dermatology Dermatomyositis Desmoid Tumour Diabetic foot ulcer (DFU) Diabetic macular oedema Diabetic nephropathy Diabetic retinopathy Differentiated thyroid cancer (DTC) Diffuse large B-cell lymphoma (DLBCL) Distal renal tubular acidosis Dravet syndrome Duchenne muscular dystrophy (DMD) Dupuytren's disease Dystrophic epidermolysis bullosa (DEB) Ear Endometrial cancer Endometriosis-associated pain Enthesitis-related arthritis Eosinophilic granulomatosis Eosinophilic granulomatosis with polyangiitis Eosinophilic oesophagitis Epilepsy Epithelial ovarian cancer Epithelial ovarian cancers Erectile dysfunction Erythropoietic protoporphyria Exocrine pancreatic insufficiency (EPI) Fabry disease Facial angiofibroma Fallopian tube cancer Familial adenomatous polyposis (FAP) Familial chylomicronaemia syndrome (FCS) Familial primary hypoalphalipoproteinemia Fatal Female Reproductive Cancer Fibrodysplasia ossificans progressiva Focal segmental glomerulosclerosis (FSGS) Follicular lymphoma Friedreich's ataxia Fungal infections Galactosemia Gastric cancer Gastro-oesophageal junction adenocarcinoma Gastro-oesophageal junction cancer Gastroenteropancreatic neuroendocrine tumour Gastroesophageal adenocarcinoma Gastrointestinal Cancer Gastrointestinal stromal tumour (GIST) Gaucher disease Generalised pustular psoriasis Generalised pustular psoriasis flares Genetic Disorders Geographic atrophy Giant cell arteritis Glaucoma Glioma Glucose transporter type 1 deficiency syndrome Glycogen storage disease type 1a GM1 gangliosidosis GM2 gangliosidosis Graft versus host disease (GvHD) Granulomatosis with polyangiitis (GPA) Grass pollen allergy Gynaecology and Obstetrics Haemophilia A Haemophilia B Hand dysfunction Head and neck cancer Heart failure (HF) Heavy menstrual bleeding Helicobacter pylori Hepatocellular carcinoma (HCC) Hereditary angioedema (HAE) Heterozygous familial hypercholesterolaemia (HeFH) Hidradenitis suppurativa (HS) High grade B cell lymphoma (HGBCL) HIV infection HIV-1 infection Hodgkin lymphoma Homozygous familial hypercholesterolaemia Homozygous familial hypercholesterolemia Hospital-acquired pneumonia Hot flushes Huntington's disease Hyperargininemia Hypereosinophilic syndrome (HES) Hyperlipidaemia Hyperphagia Hypersomnia Hypertension Hypertrophic cardiomyopathy (HCM) Hypoglycaemia Hypoparathyroidism Hypophosphataemia Hypoplasminogenaemia Hypothalamic obesity Idiopathic chronic cough Idiopathic inflammatory myopathies Idiopathic pulmonary fibrosis Idiopathic short stature or Noonan syndrome or Small for gestational age Idiopathic thrombocytopenic purpura IgA nephropathy Immune thrombocytopenia (ITP) Immune-complex membranoproliferative glomerulonephritis Immunodeficiency Influenza Inherited epidermolysis bullosa (EB) Injured gluteal musculature Insomnia Interstitial cystitis Interstitial lung disease (ILD) Invasive candidasis Iron deficiency Iron overload Irritable bowel syndrome with predominant constipation (IBS-C) Ischaemic stroke Juvenile idiopathic arthritis Juvenile psoriatic arthritis Keratoconjunctivitis sicca (dry eye disease) Leber's hereditary optic neuropathy (LHON) Lennox-Gastaut syndrome Leukocyte adhesion deficiency Long chain fatty acid oxidation disorders (LC-FAOD) Lower limb spasticity Lupus nephritis Lymphoblastic lymphoma (LBL) Lymphocytic colitis Major adverse cardiovascular events (MACE) Major cardiovascular events Major depressive disorder (MDD) Malignant hyperthermia Malignant pleural mesothelioma (MPM) Mantle cell lymphoma Marginal zone lymphoma (MZL) Mature T-cell lymphoma Medullary thyroid cancer (MTC) Melanoma Merkel cell carcinoma (MCC) Metabolic acidosis Metabolic Disorders Metachromatic leukodystrophy (MLD) Methotrexate toxicity during cancer therapy Microscopic polyangiitis (MPA) Migraine Mixed dyslipidaemia Molybdenum cofactor deficiency Type A Monocarboxylate transporter 8 deficiency (Allan-Herndon-Dudley syndrome) Motor neurone disease (MND or ALS) Mucopolysaccharidosis type IIIB (Sanfilippo B syndrome) Mucopolysaccharidosis type VII Multifocal motor neuropathy Multiple myeloma (MM) Multiple sclerosis (MS) Muscle spasticity Myasthenia gravis (MG) Mycosis fungoides or sezary syndrome Myelodysplastic syndrome (MDS) Myelofibrosis Myeloproliferative Neoplasms Myofibroblastic tumour Myopia Myotonia Myotonic dystrophy Myxoid round cell liposarcoma Narcolepsy Nasal polyps Nasopharyngeal cancer Nasopharyngeal carcinoma Neovascular age-related macular degeneration Neuroblastoma Neuroendocrine tumour Neurofibromatosis Neurogenic detrusor overactivity Neuromyelitis optica Neuromyelitis optica spectrum disorders Niemann-Pick Disease Nocturia Non-alcoholic steatohepatitis (NASH) Non-gBRCA mutated high-grade serous ovarian cancer Non-Hodgkin lymphoma (NHL) Non-malignant diseases Non-metastatic prostate cancer Non-small-cell lung cancer (NSCLC) Nose and Throat Obesity Obesity due to heart-failure Obesity due to Leptin receptor deficiency Obesity due to pro-opiomelanocortin deficiency Obesity-related heart failure Ocular hypertension Ocular inflammatory pain Oesophageal cancer Oesophageal squamous cell cancer Oesophageal squamous cell carcinoma Opioid dependence Opioid overdose Oral ulcers Orthostatic hypotension Osteoarthritic pain Osteomalacia Osteoporosis Ovarian cancer Ovarian function Overactive bladder Painful bladder syndrome Pancreatic cancer Parkinson's disease Paroxysmal nocturnal haemoglobinuria Paroxysmal nocturnal haemoglobinuria (PNH) Peanut allergy Pemphigus foliaceus Pemphigus vulgaris Peripheral arterial disease (PAD) Peripheral T-cell lymphoma (PTCL) PIK3CA-related overgrowth spectrum (PROS) Plaque psoriasis Plexiform neurofibromas Polycythaemia vera Pompe disease Post-acute myocardial infarction (MI) Post-menopausal vasomotor symptoms Post-operative inflammation Post-operative pain Post-transplant lymphoproliferative disease (PTLD) Postmenopausal osteoporosis Postnatal depression Postpartum depression Pouchitis Prevention of skeletal related events in multiple myeloma Primary axillary hyperhidrosis Primary biliary cholangitis (PBC) Primary generalised tonic-clonic seizures Primary haemophagocytic lymphohistiocytosis (HLH) Primary hypercholesterolaemia Primary hyperoxaluria Primary IgA nephropathy Primary mediastinal large B-cell lymphoma (PMBCL) Primary open-angle glaucoma primary peritoneal cancer Primary sclerosing cholangitis (PSC) Procedural sedation Progeria Progressive familial intrahepatic cholestasis (PFIC) Progressive fibrosing interstitial lung disease (PF-ILD) Progressive pulmonary fibrosis Progressive supranuclear palsy (PSP) Prostate cancer Prurigo nodularis (PN) Pruritus Psoriatic arthritis Pulmonary arterial hypertension (PAH) Pulmonary hypertension Pyruvate kinase deficiency Regeneration of cartilage Renal anaemia Renal cell carcinoma (RCC) Renal disease Resistant hypertension Respiratory dysfunction Retinal Vein Occlusion Retinitis pigmentosa Retinopathy of prematurity Rett syndrome Rheumatoid arthritis Rhinosinusitis Schizophrenia Schnitzler syndrome Serious Trouble Short bowel syndrome Sialorrhea Sickle cell anaemia Sickle cell disease (SCD) Small lymphocytic lymphoma (SLL) Small-cell lung cancer (SCLC) Soft tissue sarcoma Solid tumours Spasmodic torticollis Spinal cord injury Spinal muscular atrophy (SMA) Spinocerebellar ataxia Spondyloarthritis Squamous cell anal carcinoma Squamous cell carcinoma (SCC) Squamous cell oesophageal carcinoma Stroke Sudden sensorineural hearing loss Super-refractory status epilepticus (SRSE) Synovial sarcoma Systemic lupus erythematosus (SLE) Systemic mastocytosis Systemic sclerosis Tendon injury Tenosynovial giant cell tumour (TGCT) Thromboembolism Thrombotic microangiopathies Thrombotic thrombocytopenic purpura Thymidine kinase 2 deficiency Thyroid cancer Thyroid eye disease (TED) Transthyretin amyloid cardiomyopathy Transthyretin-mediated amyloid polyneuropathy Traumatic brain injury (TBI) Tree pollen allergy Tuberous sclerosis Type 1 diabetes Type 2 diabetes Ulcerative colitis Ulcerative proctitis Uncontrolled bleeding Upper limb spasticity Urinary incontinence Urothelial cancer Uterine Fibroids Uveal melanoma Venous leg ulcers Ventilator-associated pneumonia Visual impairment Vitiligo von Willebrand disease Vulvovaginal candidiasis Weight management WHIM syndrome Wilson's disease Wiskott-Aldrich syndrome (WAS) X-linked adrenoleukodystrophy (X-ALD) X-linked protoporphyria Check All
By clicking "subscribe" I confirm that I am happy to receive alerts.
Subscribed successfully.
