Anifrolumab is currently in clinical development for the treatment of moderately to severely active, autoantibody-positive systemic lupus erythematosus (SLE). SLE is an autoimmune disease where the body’s immune system attacks its own tissues and organs. Patients will often have periods where their symptoms flare-up and periods where their symptoms settle down. The exact causes of […]
Acute myeloid leukaemia (AML) is a type of cancer that causes the bone marrow to produce lots of immature white blood cells. It is most common in people aged 60 years and over. Symptoms of AML may include weakness, fatigue, shortness of breath, recurrent infections, prolonged bleeding, loss in appetite and unintended weight loss. Most […]
Acute myeloid leukaemia (AML) is an aggressive type of blood cancer that starts from certain types of young white blood cells called granulocytes or monocytes in the bone marrow. The bone marrow is the soft inner part of the bones, where new blood cells are made. AML usually develops over a few weeks and becomes […]
Adjuvant pembrolizumab with or without standard adjuvant treatment is in clinical development for the treatment of early-stage operable non-small cell lung cancer (NSCLC) after resection. NSCLC is the most common type of lung cancer. Early-stage lung cancer is typically treated with surgery to remove either part of or the whole of the lung, with adjuvant […]
Adrenoleukodystrophy (ALD), otherwise known as Lorenzo’s oil disease, is a rare genetic disorderlinked to the X chromosome (i.e. mainly affecting boys and men, although female carriers can exhibitsymptoms). Mutations in a gene called ABCD1 initiate a set of problems which result in the destructionof the protective sheath around nerve cells, and lead to progressive neurologic […]
Adstiladrin is currently in clinical development for the treatment of patients with high-grade non-muscle-invasive bladder cancer (NMIBC). It is being developed particularly for NMIBC that is not responsive to Bacillus Calmette-Guerin (BCG) therapy, the current main treatment option for early bladder cancer. Bladder cancer starts in the inner lining of the bladder and the most […]
Aducanumab is currently in clinical development for the treatment of mild cognitive impairment due to Alzheimer’s disease. Alzheimer’s disease is a progressive neurological disease which is caused by loss of function and death of neurones in the brain. It is the most common type of dementia. One of the early symptoms of Alzheimer’s disease is […]
ADV7103 is a combination product of potassium bicarbonate + potassium citrate extended release (i.e. the drug is released slowly over time). It is intended to treat distal renal tubular acidosis (dRTA) in adults, adolescents and children aged 6 months and older. DRTA disease occurs when the kidneys do not properly remove acids from the blood […]
Afamitresgene autoleucel is in clinical development for the treatment of advanced synovial sarcoma or myxoid/round cell liposarcoma (MRCLS) in patients who have previously had chemotherapy. Both synovial sarcoma and MRCLS are two different types of soft tissue sarcomas (STS), a rare form of cancer that develops in the tissues that connect, support and surround other […]
Acute myeloid leukaemia (AML) is a type of cancer that causes the bone marrow to produce lots of immature white blood cells. It is diagnosed in around 2,400 people in England each year, and is most common in people aged 65 years and over. Risk factors for AML include repeated exposure to benzene (usually through […]
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