ABBV-951 is currently in clinical development for the treatment of motor fluctuations in Parkinson’s Disease (PD). PD is a progressive neurological disease which is caused by a loss of nerve cells in a particular part of the brain and a reduction in the levels of the chemical messenger dopamine. Loss of these nerve cells and […]
Abemaciclib is in clinical development as an adjuvant treatment for patients with early breast cancer who have undergone surgery. Early breast cancer is where the disease is limited to the breast region and has not spread to other parts of the body. Symptoms include swelling of breast regions, breast or nipple pain, nipple retraction, change […]
Abicipar pegol is an anti‐VEGF‐A therapy in clinical development for the treatment of wet age‐related macular degeneration. Wet age‐related macular degeneration is a chronic eye disease characterised by the formation and proliferation of blood vessels in the centre of the retina (a layer of tissue in the back of the eye that senses light and […]
Abilify MyCite (aripiprazole with sensor) is in clinical development for the treatment of adults with Bipolar Disorder (BP1) and Schizophrenia (SCH). BP1 is a mental health condition that causes high and low mood swings that go on for longer periods of time, compared to usual fluctuations in mood. SCH can result in a person having […]
Abrocitinib is in development for the treatment of moderate to severe atopic dermatitis (AD) in adolescents and adults aged 12 years or over. AD is a chronic inflammatory skin disease that affects both children and adults and is characterised by redness, itchiness, and scaling of the skin. Some people only have small patches of dry […]
Fremanezumab is a new medicine under development for preventative treatment of chronic and episodic migraine. It acts by targeting a very specific type of protein called the human calcitonin gene-related peptide (CGRP) which is a well-known to be involved in migraine. Therefore, if licensed it will offer a potential new treatment option for patients with […]
Status epilepticus is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to baseline between them. Status epilepticus is categorized as early, established, refractory and super-refractory. Patients with refractory status epilepticus (RSE) have failed first and second line agents (typically benzodiazepines and […]
The treatment, rexmyelocel-T, is being developed to relieve leg pain at rest and heal leg ulcers. The treatment uses cells from bone marrow which are injected into the damaged blood vessel, where they restore existing blood vessels and create new blood vessels. By improving the blood flow in the limb, this treatment aims to improve […]
131I-omburtamab is a medicinal product that is being developed for the treatment of children with advanced neuroblastoma that has spread to membranes lining the brain and spinal cord (‘leptomeningeal metastasis’). Neuroblastoma is a rare cancer that mostly affects babies and young children. It develops from specialised nerve cells (neuroblasts) in the foetus that do not […]
177Lu-PSMA-617 is in clinical development for patients with metastatic castrationresistant prostate cancer (mCRPC) who have been previously treated with androgen receptor-directed therapy (ARDT) and a taxane-based chemotherapy. Prostate cancer is a cancer of the prostate gland and mCRPC is when the cancer has spread to parts of the body other than the prostate, and it […]
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