Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pentetrazol for Idiopathic Hypersomnia and Narcolepsy Type 2	Pentetrazol (BTD-001)	Hypersomnia , Narcolepsy	Neurology	2018	View \| Download
Perampanel (Fycompa) for Paediatric Epilepsy	Perampanel (Fycompa; E 2007; ER-155055-90)	Epilepsy	Neurology	2018	View \| Download
PLX-PAD for Critical Limb Ischaemia (with minor tissue loss) in Patients Unsuitable for Revascularisation	PLX-PAD	Critical limb ischaemia (CLI)	Cardiovascular System	2018	View \| Download
Polatuzumab vedotin in combination with rituximab and bendamustine for the treatment of diffuse large B-cell lymphoma	Bendamustine (Treanda; EP-3102; Levact; Ribomustin; bendamustine hydrochloride monohydrate; bendamustine hydrochloride) , Polatuzumab vedotin (DCDS4501A; RG7596; RG-7596; Polivy) , Rituximab (MabThera; Rituxan; RG 105)	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2018	View \| Download
PV-10 for Locally Advanced Cutaneous Melanoma	PV-10 (rose bengal sodium)	Melanoma	Skin Cancer	2018	View \| Download
PXT3003 for Charcot-Marie-Tooth Disease Type 1A	PXT-3003 (fixed dose combination: baclofen; Naltrexone hydrochloride; sorbitol)	Charcot-Marie-Tooth disease	Genetic Disorders , Neurology	2018	View \| Download
Ramucirumab for Advanced Hepatocellular Carcinoma – second line	Ramucirumab (Cyramza)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2018	View \| Download
Ranibizumab for proliferative and non-proliferative diabetic retinopathy	Ranibizumab (Lucentis Port Delivery System; Lucentis)	Diabetic retinopathy	Endocrine Nutritional and Metabolic Disorders , Ophthalmology	2018	View \| Download
Ranibizumab for Retinopathy of Prematurity – first line	Ranibizumab (Lucentis Port Delivery System; Lucentis)	Retinopathy of prematurity	Gynaecology and Obstetrics , Ophthalmology	2018	View \| Download
Ravulizumab for atypical haemolytic uraemic syndrome in adults and children – first line	Ravulizumab (ALXN1210; Ultomiris)	Atypical haemolytic uraemic syndrome (aHUS)	Haematology , Nephrology	2018	View \| Download