Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
PLX-PAD for Critical Limb Ischaemia (with minor tissue loss) in Patients Unsuitable for Revascularisation	PLX-PAD	Critical limb ischaemia (CLI)	Cardiovascular System	2018	View \| Download
Omecamtiv mecarbil for treating chronic heart failure with reduced ejection fraction	Omecamtiv Mecarbil (AMG 423; CK-1827452)	Heart failure (HF)	Cardiovascular System	2020	View \| Download
Nicardipine for treating aneurysmal subarachnoid haemorrhage	Nicardipine (NicaPlant; nicardipine hydrochloride)	Aneurysmal subarachnoid haemorrhage	Cardiovascular System	2022	View \| Download
Nerinetide for acute ischaemic stroke	Nerinetide (NA-1)	Ischaemic stroke	Cardiovascular System	2019	View \| Download
Mavacamten for hypertrophic cardiomyopathy	Mavacamten (MYK-461)	Hypertrophic cardiomyopathy (HCM)	Cardiovascular System	2021	View \| Download
Macitentan-tadalafil for treating pulmonary arterial hypertension	Macitentan-tadalafil	Pulmonary arterial hypertension (PAH)	Cardiovascular System , Respiratory System	2022	View \| Download
Macitentan for treating pulmonary arterial hypertension in children	Macitentan	Pulmonary arterial hypertension (PAH)	Cardiovascular System , Respiratory System	2022	View \| Download
Invimestrocel for Acute ischaemic stroke	Multistem(PF05285401;HLCM05;invimestrocel)	Acute ischaemic stroke	Cardiovascular System	2023	View \| Download
Inhaled treprostinil for treating pulmonary hypertension with interstitial lung disease including combined pulmonary fibrosis and emphysema	Treprostinil (Tyvaso; LIQ861; Orenitram; UT-15C; Remodulin; treprostinil sodium)	Pulmonary hypertension	Cardiovascular System , Respiratory System	2024	View \| Download
Imlifidase for kidney transplantation in highly sensitised patients with chronic kidney disease	Imlifidase (IdeS)	Chronic kidney disease (CKD)	Cardiovascular System , Nephrology	2019	View \| Download