Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Nivolumab in combination with ipilimumab for malignant pleural mesothelioma – first line	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Malignant pleural mesothelioma (MPM)	Lung and Respiratory Cancer	2019	View \| Download
Nivolumab in combination with cisplatin and fluorouracil for oesophageal cancer – first-line	5-Fluorouracil , Cisplatin (Platinol) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Oesophageal cancer	Head and Neck Cancer	2019	View \| Download
Nivolumab in combination with cabozantinib for metastatic renal cell carcinoma – first-line	Cabozantinib (XL-184; Cabometyx; Cometriq; XL 184) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Renal cell carcinoma (RCC)	Renal Cancer	2019	View
Nivolumab in addition to temozolomide and radiotherapy for MGMT-methylated glioblastoma in newly diagnosed adults - first line	Nivolumab (Opdivo; BMS-936558; ONO-4538) , Radiation , Temozolomide (Temodar; Temodal; SCH 52365)	Glioma	Neurological Cancer	2019	View \| Download
Nivolumab for platinum-resistant advanced or recurrent ovarian cancer	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Nivolumab for oesophageal or gastro-oesophageal junction cancer - adjuvant	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Gastro-oesophageal junction cancer , Oesophageal cancer	Gastrointestinal Cancer , Head and Neck Cancer	2019	View \| Download
Nivolumab for high risk invasive urothelial carcinoma - adjuvant	Nivolumab (Opdivo; BMS-936558; ONO-4538)	Urothelial cancer	Urological Cancer	2019	View \| Download
Nivolumab and relatlimab for untreated advanced or metastatic melanoma – first line	Nivolumab (Opdivo; BMS-936558; ONO-4538) , Relatlimab (BMS-986016; Anti-LAG-3)	Melanoma	Skin Cancer	2019	View \| Download
Nitisinone for Alkaptonuria	Nitisinone (Orfadin; SYN118)	Alkaptonuria	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Niraparib for advanced ovarian, fallopian tube or primary peritoneal cancer - maintenance therapy	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download