Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 200 Results

Title
Intervention Indication Therapeutic Area Year Actions
Concizumab for treating haemophilia A and haemophilia B Concizumab (NN-7415; mAb-2021; NNC-0172-0000-2021; NNC-0172-2021; NNC-172-2021) Haemophilia A , Haemophilia B Haematology 2022 View  |  Download
Crizanlizumab for the prevention of recurrent vaso-occlusive crises in children with sickle cell disease Crizanlizumab (SEG101; Adakveo) Sickle cell disease (SCD) Haematology 2022 View  |  Download
Crovalimab for treatment of paroxysmal nocturnal haemoglobinuria Crovalimab Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2022 View  |  Download
Dabrafenib with trametinib for treating paediatric BRAF V600 mutated high-grade or low-grade glioma Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide) Glioma Neurological Cancer 2022 View  |  Download
Danicopan with eculizumab or ravulizumab for treating paroxysmal nocturnal haemoglobinuria Danicopan (ACH-0144471; ACH-4471; ALXN2040) , Ravulizumab (ALXN1210; Ultomiris) Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2022 View  |  Download
Daratumumab for the treating high-risk smouldering multiple myeloma Daratumumab (Darzalex; JNJ-54767414) Multiple myeloma (MM) Haematological Cancer and Lymphomas 2022 View  |  Download
Daratumumab with bortezomib, lenalidomide and dexamethasone for previously untreated transplant eligible multiple myeloma Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid) Multiple myeloma (MM) Haematological Cancer and Lymphomas 2022 View  |  Download
Denosumab biosimilar for treating postmenopausal osteoporosis Denosumab biosimilar Postmenopausal osteoporosis Musculoskeletal System 2022 View  |  Download
Dersimelagon for previously untreated erythropoietic protoporphyria and X-linked protoporphyria Dersimelagon Erythropoietic protoporphyria , X-linked protoporphyria Dermatology , Haematology 2022 View  |  Download
Dexmedetomidine film for agitation associated with bipolar disorder Dexmedetomidine Bipolar disorder Mental and Behavioural Health 2022 View  |  Download
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