Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
SAGE-547 for super-refractory status epilepticus	Brexanolone (SAGE-547; Zulresso)	Super-refractory status epilepticus (SRSE)	Neurology	2017	View \| Download
SAR443820 for treating amyotrophic lateral sclerosis (ALS)	SAR443820 (DNL788)	Amyotrophic lateral sclerosis	Neurology	2023	View \| Download
Sarizotan for Respiratory Symptoms Associated Rett Syndrome	Sarizotan (EMD-128130)	Rett syndrome	Genetic Disorders , Neurology	2018	View \| Download
Selumetinib for neurofibromatosis type 1	Selumetinib (AZD6244; ARRY-142886)	Neurofibromatosis	Neurology	2019	View \| Download
Selumetinib for treating symptomatic, inoperable plexiform neurofibromas associated with type 1 neurofibromatosis in adults	Selumetinib (AZD6244; ARRY-142886)	Plexiform neurofibromas	Neurological Cancer , Neurology	2023	View \| Download
Sodium phenylbutyrate-ursodoxicoltaurine for treating amyotrophic lateral sclerosis	Sodium phenylbutyrate-ursodoxicoltaurine	Amyotrophic lateral sclerosis	Neurology	2022	View \| Download
STS101 for the acute treatment of migraine	STS-101 (TO-2070, dihydroergotamine)	Migraine	Neurology	2022	View \| Download
Tideglusib for congenital myotonic dystrophy	Tideglusib (AMO-02; Zentylor; Nypta; NP031112)	Myotonic dystrophy	Genetic Disorders , Musculoskeletal System , Neurology	2020	View \| Download
Tiratricol for treating monocarboxylate transporter 8 deficiency (Allan-Herndon-Dudley syndrome)	Tiratricol	Monocarboxylate transporter 8 deficiency (Allan-Herndon-Dudley syndrome)	Genetic Disorders , Neurology	2022	View \| Download
Tofersen for the treatment of amyotrophic lateral sclerosis caused by mutations in the SOD1 gene	Tofersen sodium (BIIB067)	Motor neurone disease (MND or ALS)	Neurology	2020	View \| Download