Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Atezolizumab with cabozantinib for previously treated metastatic castration-resistant prostate cancer	Atezolizumab (Tecentriq; MPDL3280A) , Cabozantinib (XL-184; Cabometyx; Cometriq; XL 184)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Atezolizumab with cabozantinib for treating metastatic non-small-cell lung cancer after platinum-containing chemotherapy and one programmed death-ligand 1 checkpoint inhibitor	Atezolizumab (Tecentriq; MPDL3280A) , Cabozantinib (XL-184; Cabometyx; Cometriq; XL 184)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Atezolizumab with chemotherapy for treating recurrent triple-negative breast cancer	Atezolizumab (Tecentriq; MPDL3280A) , Chemotherapy	Breast cancer	Breast Cancer	2022	View \| Download
Atezolizumab with paclitaxel and carboplatin for previously untreated advanced endometrial cancer	Atezolizumab (Tecentriq; MPDL3280A) , Carboplatin (Paraplatin) , Paclitaxel (Taxol; paclitaxel albumin)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download
Atezolizumab with platinum-based chemotherapy and bevacizumab for epithelial ovarian cancer or fallopian tube cancer or primary peritoneal cancer	Atezolizumab (Tecentriq; MPDL3280A) , Bevacizumab (Avastin; R 435; RG 405; RG 435) , Chemotherapy	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2022	View \| Download
Atogepant for prevention of migraine	Atogepant (AGN-241689; MK-8031)	Migraine	Neurology	2022	View \| Download
Avacincaptad pegol for the treatment of geographic atrophy secondary to age-related macular degeneration	Avacincaptad pegol	Age-related macular degeneration (AMD) , Geographic atrophy	Ophthalmology	2023	View \| Download
Avacopan in addition to standard of care for ANCA-associated vasculitis	Avacopan (CCX168)	Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)	Cardiovascular System , Immunology	2018	View \| Download
Avalglucosidase alfa for late-onset Pompe disease	Avalglucosidase alfa (neoGAA; GZ-402666)	Pompe disease	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Avapritinib for advanced systemic mastocytosis	Avapritinib (BLU-285; Ayvakit)	Systemic mastocytosis	Immunology	2020	View \| Download