Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Trastuzumab deruxtecan for treating previously untreated locally advanced or metastatic non-small cell lung cancer with HER2 mutations	Trastuzumab deruxtecan (DS-8201a; Enhertu)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2024	View \| Download
Trastuzumab deruxtecan for unresectable or metastatic HER2-low (HR+/-) breast cancer – after chemotherapy	Trastuzumab deruxtecan (DS-8201a; Enhertu)	Breast cancer	Breast Cancer	2021	View \| Download
Trastuzumab deruxtecan neoadjuvant therapy for high-risk HER2-positive early stage breast cancer	Trastuzumab deruxtecan (DS-8201a; Enhertu)	Breast cancer	Breast Cancer	2023	View \| Download
Trastuzumab duocarmazine for third-line treatment of HER2-positive unresectable metastatic breast cancer	Trastuzumab duocarmazine	Breast cancer	Breast Cancer	2023	View \| Download
Trastuzumab Emtansine for HER2-positive breast cancer - adjuvant	Trastuzumab Emtansine (Kadcyla; T-DM1; PRO132365)	Breast cancer	Breast Cancer	2018	View \| Download
Trastuzumab emtansine in combination with pertuzumab for HER2-positive early breast cancer - adjuvant therapy	Pertuzumab (Perjeta; R-1273) , Trastuzumab Emtansine (Kadcyla; T-DM1; PRO132365)	Breast cancer	Breast Cancer	2019	View \| Download
Treosulfan in combination with Fludarabine for Malignant and Non-Malignant diseases - prior to stem cell transplantation	Fludarabine (fludarabine phosphate) , Treosulfan (Ovastat)	Acute myeloid leukaemia (AML) , Myelodysplastic syndrome (MDS)	Haematological Cancer and Lymphomas	2018	View \| Download
Treosulfan in combination with fludarabine for paediatric non-malignant disease before allogeneic stem cell transplant	Fludarabine (fludarabine phosphate) , Treosulfan (Ovastat)	Non-malignant diseases	Endocrine Nutritional and Metabolic Disorders , Haematology , Immunology	2019	View \| Download
Treprostinil diethanolamine for treating pulmonary arterial hypertension	Treprostinil diethanolamine	Paroxysmal nocturnal haemoglobinuria	Cardiovascular System , Respiratory System	2022	View \| Download
Treprostinil for chronic thromboembolic pulmonary hypertension	Hybrid treprostinil (Trepulmix)	Chronic thromboembolic pulmonary hypertension (CTEPH)	Cardiovascular System	2020	View \| Download