Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Daratumumab in addition to cyclophosphamide, bortezomib and dexamethasone for newly diagnosed systemic amyloid light-chain amyloidosis	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Cyclophosphamide (Procytox; cyclophosphamide monohydrate) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate)	Amyloidosis	Endocrine Nutritional and Metabolic Disorders	2020	View \| Download
Daratumumab in addition to Bortezomib, Thalidomide and Dexamethasone for newly diagnosed Multiple Myeloma	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Thalidomide (Taldo)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Daratumumab in addition to bortezomib, lenalidomide and dexamethasone for multiple myeloma – first line	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
Daratumumab for the treating high-risk smouldering multiple myeloma	Daratumumab (Darzalex; JNJ-54767414)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2022	View \| Download
Daratumumab (subcutaneous injection) for multiple myeloma	Daratumumab (Darzalex; JNJ-54767414)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2019	View \| Download
Daratumumab (Darzalex) with lenalidomide and dexamethasone for multiple myeloma – first line	Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download
Dapsone for treating COVID-19	Dapsone (PULM-001;Pulmonem)	COVID-19	Respiratory System	2023	View \| Download
Daprodustat for anaemia associated with chronic kidney disease	Daprodustat (GSK1278863)	Anaemia	Cardiovascular System , Haematology , Nephrology	2021	View \| Download
Dapagliflozin for heart failure with preserved ejection fraction	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Heart failure (HF)	Cardiovascular System	2019	View \| Download
Dapagliflozin for chronic kidney disease	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Chronic kidney disease (CKD)	Cardiovascular System , Nephrology	2020	View \| Download