Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 1139 Results

Title
Intervention Indication Therapeutic Area Year Actions
Danicopan with eculizumab or ravulizumab for treating paroxysmal nocturnal haemoglobinuria Danicopan (ACH-0144471; ACH-4471; ALXN2040) , Ravulizumab (ALXN1210; Ultomiris) Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2022 View  |  Download
Dabrafenib with Trametinib with adjuvant therapy for treating advanced BRAF V600 mutation-positive melanoma in adolescents Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide) Melanoma Skin Cancer 2023 View  |  Download
Dabrafenib with trametinib for treating paediatric BRAF V600 mutated high-grade or low-grade glioma Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide) Glioma Neurological Cancer 2022 View  |  Download
Dabrafenib with trametinib for treating metastatic or unresectable BRAF V600 mutation-positive melanoma in adolescents Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide) Melanoma Skin Cancer 2023 View  |  Download
Dabigatran Etexilate (Pradaxa) for Secondary Stroke Prevention in Patients with Embolic Stroke of Undetermined Source – First Line Dabigatran etexilate (Pradaxa) Ischaemic stroke Cardiovascular System 2017 View  |  Download
Cysteamine bitartrate for cystic fibrosis exacerbations Cysteamine bitartrate (Procysbi; RP103; Lynovex; NM001; Cystadrops; Mercaptamine) Cystic fibrosis Genetic Disorders , Respiratory System 2018 View  |  Download
Cysteamine bitartrate (Procysbi) delayed release for Huntington’s Disease Cysteamine bitartrate (Procysbi; RP103; Lynovex; NM001; Cystadrops; Mercaptamine) Huntington's disease Genetic Disorders , Neurology 2017 View  |  Download
CTX001 for transfusion-dependent beta-thalassaemia CTX001 Beta thalassemia Genetic Disorders , Haematology 2021 View  |  Download
CTX001 for severe sickle cell disease CTX001 Leukocyte adhesion deficiency , Sickle cell disease (SCD) Haematology , Immunology 2021 View  |  Download
Crovalimab for treatment of paroxysmal nocturnal haemoglobinuria Crovalimab Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2022 View  |  Download
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