Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Crizotinib (Xalcori) for locally advanced or metastatic Non‐Small Cell Lung Cancer (NSCLC)	Crizotinib (Xalkori; PF-02341066; Xalkor)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2018	View \| Download
Crizanlizumab for the prevention of recurrent vaso-occlusive crises in children with sickle cell disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell disease (SCD)	Haematology	2022	View \| Download
Crizanlizumab (formerly SelG1) for Sickle Cell Disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell anaemia	Haematology	2017	View \| Download
Crenolanib for Advanced or Metastatic Gastrointestinal Stromal Tumours (GISTs) with the D842V Mutation in the PDGFRA Gene	Crenolanib (CP-868; CP-868596)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2018	View \| Download
Concizumab for treating haemophilia A and haemophilia B	Concizumab (NN-7415; mAb-2021; NNC-0172-0000-2021; NNC-0172-2021; NNC-172-2021)	Haemophilia A , Haemophilia B	Haematology	2022	View \| Download
Conbercept for neovascular age-related macular degeneration	Conbercept (KH902)	Age-related macular degeneration (AMD)	Ophthalmology	2021	View \| Download
Cobolimab with dostarlimab and docetaxel for advanced non-small-cell lung cancer after anti-PD-L1 therapy and chemotherapy	Cobolimab , Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous) , Dostarlimab (TSR-042; Jemperli)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Clostridium botulinum type A toxin-haemagglutinin complex (Dysport) for urinary incontinence	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Neurogenic detrusor overactivity , Urinary incontinence	Neurology , Urology	2021	View \| Download
Clostridium botulinum Type A toxin (Dysport) for Spasmodic torticollis	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Spasmodic torticollis	Musculoskeletal System , Neurology	2017	View \| Download
Clostridium botulinum neurotoxin A (Xeomin) for lower limb spasticity due to cerebral palsy – first line	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Lower limb spasticity	Musculoskeletal System , Neurology	2017	View \| Download