Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Dabrafenib with Trametinib with adjuvant therapy for treating advanced BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download
Dabrafenib with trametinib for treating metastatic or unresectable BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download
Cobolimab with dostarlimab and docetaxel for advanced non-small-cell lung cancer after anti-PD-L1 therapy and chemotherapy	Cobolimab , Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous) , Dostarlimab (TSR-042; Jemperli)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Cladribine for treating relapsing-remitting multiple sclerosis	Cladribine	Multiple sclerosis (MS)	Neurology	2023	View \| Download
Cipaglucosidase alfa/miglustat for treating children and adolescents with late-onset Pompe disease	Cipaglucosidase alfa/miglustat (AT-GAA;;Zavesca,;OGT 918;BBDF101)	Pompe disease	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2023	View \| Download
Ciclosporin ophthalmic solution for treating moderate-to-severe keratoconjunctivitis sicca (dry eye disease)	Ciclosporin ophthalmic solution	Keratoconjunctivitis sicca (dry eye disease)	Ophthalmology	2023	View \| Download
Capivasertib with paclitaxel for previously untreated locally advanced or metastatic triple-negative breast cancer	Capivasertib , Paclitaxel (Taxol; paclitaxel albumin)	Breast cancer	Breast Cancer	2023	View \| Download
Capivasertib with fulvestrant for HR+/HER2- locally advanced or metastatic breast cancer	Capivasertib , Fulvestrant (Faslodex)	Breast cancer	Breast Cancer	2023	View \| Download
Canagliflozin for type 2 diabetes mellitus in children and adolescents	Canagliflozin (Invokana; canagliflozin hemihydrate)	Type 2 diabetes	Endocrine Nutritional and Metabolic Disorders	2023	View \| Download
Cabozantinib with nivolumab and ipilimumab for previously untreated advanced or metastatic renal cell carcinoma	Cabozantinib (XL-184; Cabometyx; Cometriq; XL 184) , Ipilimumab (Yervoy; BMS 734016; MDX 101) , Nivolumab (Opdivo; BMS-936558; ONO-4538)	Renal cell carcinoma (RCC)	Renal Cancer	2023	View \| Download