Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Empagliflozin for treating chronic kidney disease	Empagliflozin (Jardiance; DINAMO)	Chronic kidney disease (CKD)	Cardiovascular System , Nephrology	2022	View \| Download
Empagliflozin for the treatment of acute myocardial infarction to reduce heart failure and mortality	Empagliflozin (Jardiance; DINAMO)	Heart failure (HF)	Cardiovascular System	2022	View \| Download
Empagliflozin for Chronic Heart Failure with Preserved Ejection Fraction	Empagliflozin (Jardiance; DINAMO)	Heart failure (HF)	Cardiovascular System	2021	View \| Download
Emicizumab for mild or moderate haemophilia A	Emicizumab (Hemlibra)	Haemophilia A	Haematology	2021	View \| Download
Emapalumab for Primary Haemophagocytic Lymphohistiocytosis	Emapalumab (NI-0501; Gamifant)	Primary haemophagocytic lymphohistiocytosis (HLH)	Genetic Disorders , Immunology	2018	View \| Download
Elranatamab monotherapy or with daratumumab for previously treated relapsed or refractory multiple myeloma	Daratumumab (Darzalex; JNJ-54767414) , Elranatamab (PF-06863135)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas , Skin Cancer	2024	View \| Download
Elranatamab for treating relapsed /refractory multiple myeloma	Elranatamab (PF-06863135)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2021	View \| Download
Elotuzumab in combination with pomalidomide and low-dose dexamethasone for relapsed and refractory multiple myeloma – third line	Dexamethasone (dexamethasone sodium metasulfobenzoate) , Elotuzumab (Empliciti; BMS-901608; HuLuc63) , Pomalidomide (Imnovid; CC-4047; Pomalyst)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Elinzanetant for the treatment of moderate to severe vasomotor symptoms (hot flashes) associated with the menopause	Elinzanetant	Post-menopausal vasomotor symptoms	Women's Health	2023	View \| Download
Elexacaftor/tezacaftor/ivacaftor and ivacaftor for treating cystic fibrosis without an F508del mutation and with an ELX/TEZ/IVA-responsive mutation in the CFTR gene in patients aged 6 years and older	Ivacaftor (Kalydeco; VX-770) , Kaftrio (fixed dose combination: Elexacaftor; Tezacaftor; Ivacaftor)	Cystic fibrosis	Genetic Disorders , Respiratory System	2023	View \| Download