Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Avatrombopag for chemotherapy induced thrombocytopenia in patients with nonhaematological cancers	Avatrombopag (Doptelet; E5501; avatrombopag maleate)	Chemotherapy-induced thrombocytopenia	Female Reproductive Cancer , Haematology , Lung and Respiratory Cancer , Toxicology , Urological Cancer	2020	View \| Download
Avapritinib for unresectable or metastatic gastrointestinal stromal tumours (GIST) who have been treated with at least 3 prior lines of therapy and GIST harbouring the PDGFRA D842V mutation regardless of prior therapy	Avapritinib (BLU-285; Ayvakit)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2019	View \| Download
Avapritinib for advanced systemic mastocytosis	Avapritinib (BLU-285; Ayvakit)	Systemic mastocytosis	Immunology	2020	View \| Download
Avalglucosidase alfa for late-onset Pompe disease	Avalglucosidase alfa (neoGAA; GZ-402666)	Pompe disease	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Avacopan in addition to standard of care for ANCA-associated vasculitis	Avacopan (CCX168)	Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)	Cardiovascular System , Immunology	2018	View \| Download
Avacincaptad pegol for the treatment of geographic atrophy secondary to age-related macular degeneration	Avacincaptad pegol	Age-related macular degeneration (AMD) , Geographic atrophy	Ophthalmology	2023	View \| Download
Atogepant for prevention of migraine	Atogepant (AGN-241689; MK-8031)	Migraine	Neurology	2022	View \| Download
Atezolizumab-tiragolumab for locally advanced, recurrent, or metastatic PD-L1 selected solid tumours	Atezolizumab-tiragolumab	Solid tumours	Lung and Respiratory Cancer	2024	View \| Download
Atezolizumab with platinum-based chemotherapy and bevacizumab for epithelial ovarian cancer or fallopian tube cancer or primary peritoneal cancer	Atezolizumab (Tecentriq; MPDL3280A) , Bevacizumab (Avastin; R 435; RG 405; RG 435) , Chemotherapy	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2022	View \| Download
Atezolizumab with paclitaxel and carboplatin for previously untreated advanced endometrial cancer	Atezolizumab (Tecentriq; MPDL3280A) , Carboplatin (Paraplatin) , Paclitaxel (Taxol; paclitaxel albumin)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download