Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 130 Results

Intervention Indication Therapeutic Area Year Actions
A4250 for progressive familial intrahepatic cholestasis Odevixibat (A4250) Progressive familial intrahepatic cholestasis (PFIC) Genetic Disorders , Hepatology 2017 View  |  Download
Abemaciclib in combination with fulvestrant for advanced or metastatic breast cancer after prior endocrine therapy Abemaciclib (LY2835219; Verzenio; CC-115) , Fulvestrant (Faslodex) Breast cancer Breast Cancer 2017 View  |  Download
Alpelisib in Combination with Fulvestrant for Advanced HR Positive, HER2-negative Breast Cancer in Men and Postmenopausal Women Alpelisib (BYL719; Piqray) , Fulvestrant (Faslodex) Breast cancer Breast Cancer 2017 View  |  Download
ALXN 1210 for Paroxysmal Nocturnal Haemoglobinuria – First Line Ravulizumab (ALXN1210; Ultomiris) Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2017 View  |  Download
AR101 peanut allergy immunotherapy for adult and paediatric patients Palforzia (AR101) Peanut allergy Immunology 2017 View  |  Download
Arimoclomol for Niemann-Pick Disease type C - add-on therapy Arimoclomol (BRX-345) Niemann-Pick Disease Endocrine Nutritional and Metabolic Disorders , Genetic Disorders , Neurology 2017 View  |  Download
Asinercept (Apocept) for glioblastoma multiforme for first or second line Asunercept (Apocept; APG101) Glioma Neurological Cancer 2017 View  |  Download
Atezolizumab (Tecentriq) and Cobimetinib (Cotellic) for advanced/metastatic colorectal cancer - third line Atezolizumab (Tecentriq; MPDL3280A) , Cobimetinib (Cotellic; GDC-0973; cobimetinib hemifumarate) Colorectal cancer Gastrointestinal Cancer , Oncology 2017 View  |  Download
Avelumab for gastric and gastroesophageal junction adenocarcinoma – third line Avelumab (Bavencio; MSB-0010718C) Gastric cancer , Gastro-oesophageal junction cancer Gastrointestinal Cancer 2017 View  |  Download
Axicabtagene ciloleucel IV for relapsed/refractory acute lymphoblastic leukaemia in children and adolecents (aged 2-21 years) – second line Brexucabtagene autoleucel (Tecartus; KTE-X19) Acute lymphoblastic leukaemia (ALL) Haematological Cancer and Lymphomas 2017 View  |  Download
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